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Behavioral problems in children with autism spectrum disorder with and without co-occurring intellectual disability

机译:自闭症谱系疾病儿童的行为问题,无需共同发生智力障碍

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BackgroundAutism spectrum disorder (ASD), intellectual disability (ID), and behavioral problems commonly co-occur, leading to increased impairment, diagnostic confusion, and treatment delays. Using data from a large surveillance population of children with ASD, the objectives of the present study were to compare the relative risk of common behavioral problems in children with ASD, with and without co-occurring intellectual disability. MethodsData from the Autism and Developmental Disabilities Monitoring (ADDM) Network (2006–2010) on 9378 8-year-old children who met case definition for ASD and had cognitive test scores and information on behavioral problems were analyzed using frequency measures, risk ratios, chi-squared tests, and trend tests. ResultsChildren with ASD with and without ID had on average six co-occurring behavioral problems. The relative risk (RR) of self-injurious behaviors, unusual fear responses, and eating abnormalities increased with increasing cognitive impairment among children with ASD and ID (allp<0.001). Conversely, RR of mood (p<0.001) and sleep abnormalities (p=0.013) declined with increasing levels of cognitive impairment. ConclusionsChildren with ASD and ID are at greater risk of some behavioral problems and lower risk of others as compared to children with ASD only. Successful interventions depend on understanding the complex interactions between co-occurring neurodevelopmental and behavioral problems.
机译:背景谱紊乱(ASD),智力残疾(ID)和行为问题通常共同发生,导致损伤,诊断混淆和治疗延误增加。使用来自ASD的儿童的大型监测群体的数据,本研究的目标是比较亚本语儿童常见行为问题的相对风险,无关,无需共同发生智力残疾。方法来自自闭症和发育障碍的监测(ADDM)网络(2006-2010)在9378年的8岁儿童,使用频率测量分析了认知测试评分的案例定义和有关行为问题的信息,风险比率, Chi-Squared测试和趋势测试。与ASD的结果抚平罗密斯平均平均六种共同发生的行为问题。随着ASD和ID的儿童的儿童的认知障碍增加,自我伤害行为的相对风险(RR)增加了不矛盾的行为,不寻常的恐惧反应和饮食异常(ALLP <0.001)。相反,随着认知障碍水平的增加,情绪(P <0.001)和睡眠异常(P = 0.013)下降。结论与ASD和ID的结论少女较大的风险与仅限ASD的儿童相比,其他行为问题的风险和较低的风险。成功的干预措施依赖于了解共同发生的神经发育和行为问题之间的复杂相互作用。

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