Hydroxychloroquine During Cancer Therapy

Michael F. Marmor

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Hydroxychloroquine During Cancer Therapy

机译：癌症治疗期间的羟基氯喹

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The article in this issue by Sharma et al, on accelerated hydroxychloroquine (HCQ) retinopathy during breast cancer therapy, is important in several respects. It highlights the growing use of HCQ as a chemotherapeutic agent; it highlights concerns about drug interactions (especially docetaxel and taxanes); it reviews characteristic syndrome of HCQ retinopathy, which is at the core of understanding these relationships; and it reminds us that visual loss must be balanced against other medical factors.

机译：在乳腺癌治疗期间，Sharma等人在乳腺癌治疗期间的加速羟基氯喹（HCQ）视网膜病变，在乳腺癌癌症治疗中，这是重要的。它突出了HCQ作为化学治疗剂的越来越多的使用; 它突出了对药物互动的担忧（特别是多西紫杉醇和紫杉烷）; 它评论了HCQ视网膜病的特征综合征，这是理解这些关系的核心; 它提醒我们，必须对其他医疗因素均衡视力损失。

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《Retinal cases & brief reports》 |2019年第2期|共3页
作者
Michael F. Marmor;
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作者单位

Department of Ophthalmology Syers Eye Institute Stanford University School of Medicine Palo Alto;

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正文语种 eng
中图分类眼科学;
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1. Hydroxychloroquine During Cancer Therapy [J] . Michael F. Marmor Retinal cases & brief reports . 2019,第2期

机译：癌症治疗期间的羟基氯喹
2. Evidence-based complementary treatment of pancreatic cancer: a review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins, metformin, curcumin, and aspirin [J] . Stephen Bigelsen Cancer Management and Research . 2018,第2期

机译：基于证据的胰腺癌补充治疗：包括paricalcitol，羟氯喹，静脉注射维生素C，他汀类药物，二甲双胍，姜黄素和阿司匹林在内的辅助疗法的综述
3. Enhanced bacterial cancer therapy with hydroxychloroquine liposomes [J] . Park Kinam Journal of Controlled Release: Official Journal of the Controlled Release Society . 2018,第期

机译：增强羟基氯喹硫吡啉的细菌癌疗法
4. Part V Multimodal Therapy of GEJ Cancer Multimodal Therapy of GEJ Cancer: When is the Definitive Radiochemotherapy the Treatment of Choice? [C] . Michael Stahl St. Gallen EORTC Gastrointestinal Cancer Conference . 2012

机译：GEJ癌多峰治疗GEJ癌的v v多峰治疗：最终放射性化疗的治疗何时选择？
5. Cancer Incidence, Mortality, and Immunotherapy Outcomes in Relation to Sleep Problems: Results from Cardiovascular Health Study and a Cancer Immunotherapy Cohort [D] . Sillah, Arthur. 2021

机译：与睡眠问题有关的癌症发病，死亡率和免疫疗法结果：心血管健康研究和癌症免疫治疗队列的结果
6. The COVIRL-001 Trial: A multicentre prospective randomised trial comparing standard of care (SOC) alone SOC plus hydroxychloroquine monotherapy or SOC plus a combination of hydroxychloroquine and azithromycin in the treatment of non- critical SARS-CoV-2 PCR-positive population not requiring immediate resuscitation or ventilation but who have evidence of clinical decline: A structured summary of a study protocol for a randomised controlled trial [O] . Eoin Feeney, Deborah Wallace, Aoife Cotter, 2020

机译：COVIRL-001试验：一项多中心前瞻性随机试验比较了单独护理标准（SOC）SOC加羟氯喹单一疗法或SOC加羟氯喹和阿奇霉素联合治疗非关键SARS-CoV-2 PCR-不需要立即复苏或通气但有临床下降迹象的阳性人群：一项随机对照试验研究方案的结构摘要
7. Chemotherapy is one of the therapies for cancer patients that cause some side effects, one of them is nausea and vomiting. Nausea and vomiting are still felt by patients even though they take antiemetics. Nausea dan vomiting can cause fluid and electrolyte imbalance. The aim of this study was to analysis the effect of combination acupressure wristband and antiemetic among chemotherapy induced nausea vomiting (CINV) on breast cancer patients. This research used quasi experimental research method, with a pre-post test with the control group. The sampling techniques was consecutive sampling with 25 respondents both in intervention group and control group. In the intervention group had received an acupressure wristband. CINV measured on the second day until fourth day after chemotherapy. Nausea and vomiting score were measured twice a day by a telemonitoring methode by Rhodes Index Nausea, Vomiting and Retching (INVR) questionaire. Data were analyzed by paired t-test, independent t-test, Wilcoxon test and Mann Whitney. The result of this study showed that acupressure wristband significantly reduce the chemotherapy induced nausea and vomit (p value = 0.000). The use of acupressure wristband combined with antiemetic therapy can significantly decrease chemotherapy induced nausea and vomiting in breast cancer patients. Acupressure wristband recommended for consideration nursing intervention in treating breast cancer patients who experience nausea and vomiting. [O] . Endah Fatma 2018

机译：化疗是癌症患者的疗法之一，导致一些副作用，其中一个是恶心和呕吐。患者仍然感受到恶心和呕吐，即使他们服用助性学。恶心丹呕吐会导致液体和电解质不平衡。本研究的目的是分析组合组合腕带和抑制在乳腺癌患者中的诱导恶心呕吐（CINV）的影响。本研究使用了准实验研究方法，用对照组进行了预先测试。采样技术是在干预组和对照组中进行25名受访者的连续抽样。在干预组中，收到了一名腕带。 Cinv在化疗后第四天测量。通过罗得岛指数恶心，呕吐和转换（INVR）问卷，每天测量恶心和呕吐分数。通过配对的T检验，独立的T检验，Wilcoxon测试和Mann Whitney分析数据。该研究的结果表明，Acuruce腕带显着降低化疗诱导的恶心和呕吐物（P值= 0.000）。使用Acu压抑腕带与止吐疗法相结合，可以显着降低乳腺癌患者诱导的恶心和呕吐。 Acu压痕腕带推荐用于治疗体验恶心和呕吐的乳腺癌患者的护理干预。

Hydroxychloroquine During Cancer Therapy

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