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首页> 外文期刊>Radiation Physics and Chemistry >Conversion Coefficients of equivalent and effective doses in terms of air kerma for computational scenarios of Total Body Irradiation in lying-down patients
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Conversion Coefficients of equivalent and effective doses in terms of air kerma for computational scenarios of Total Body Irradiation in lying-down patients

机译：在卧室卧室总体辐射的计算场景的空气Kerma方面转换系数等效和有效剂量的转换系数

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摘要

This study aimed to calculate the Conversion Coefficients (CC) of Equivalent and Effective doses by air kerma considering Total Body Irradiation scenarios with Varian linear accelerator with photon beams energy of 4, 6, 10, 15, 18, and 25 MV. The simulations were performed in the MCNPX code and the University of Florida (UF) phantoms were used to represent exposed lying down adult patients in the AP, PA, RLAT, and LLAT irradiation geometries. Lead attenuators were inserted in the scenarios for the preservation of organs of risk and their contribution were analyzed for CC. For most counts, the statistical uncertainty was approximately 5%. For the gonads, CC values for the male phantom decreased with the increase of energy in the AP geometry, which did not occur for the female phantom. As the beam becomes more penetrating, the ovary absorbs more energy because of its internal position. Considering the lung, an organ of risk in TBI, the insertion of the attenuators in the scenarios caused the CC values to reduce by more than 30%. For organs and tissues such as skin and male breasts, the attenuators caused the dose to increase. As for the active bone marrow, which is the TBI target tissue, it was not possible to obtain a good estimate for CC at 15, 18, and 25 MV due to a limitation of the method used to calculate the dose in the bone areas. Nevertheless, for lower energies the CC values for the marrow were valid.
机译：本研究旨在通过空气Kerma计算总体照射场景的空气Kerma的转换系数（CC），其具有4,6,10,15,18和25mV的光子束能量的varian线性加速器。在MCNPX码中进行了模拟，佛罗里达大学（UF）幻影用于代表AP，PA，RLAT和LLAT辐照几何形状的暴露躺着的成年患者。铅衰减器被插入了维护风险器官的情况下，并对CC分析了它们的贡献。对于大多数计数，统计不确定性约为5％。对于GONADS，雄性模型的CC值随着AP几何中的能量的增加而降低，这对女性幻影没有发生。由于光束变得更加渗透，因此由于其内部位置，卵巢吸收更多的能量。考虑到肺部，TBI的风险器官，在情景中插入衰减器导致CC值降低超过30％。对于诸如皮肤和雄性乳房等器官和组织，衰减器导致剂量增加。对于作为TBI靶组织的活性骨髓，由于用于计算骨区域中的剂量的方法的限制，不可能在15,18和25mV下获得良好的CC估计。尽管如此，对于较低的能量，骨髓的CC值有效。

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