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Surgical versus non‐surgical treatment of actinic cheilitis: A systematic review and meta‐analysis

机译:手术与非手术治疗光化杂质炎:系统审查和荟萃分析

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Abstract Objective The aim of this systematic review was to compare outcomes between surgical and non‐surgical treatment of actinic cheilitis ( AC ). Materials and Methods A systematic review and meta‐analysis based on the Preferred Reporting Items for Systematic reviews and Meta‐Analyses guideline were performed. A search of PubMed/ MEDLINE , Web of Science, and Cochrane Library databases was conducted. Articles were selected based on the inclusion criteria: randomized clinical trials, prospective/retrospective studies, and case series with at least 10 patients, with a minimum follow‐up period of 6?months. A weighted remission rate ( RER ) and recurrence rate ( RR ) with a 95% confidence interval was performed. Data analysis was performed using a comprehensive meta‐analysis software. Results A total of 283 AC s in 10 studies were included. About 2.5% surgically treated cases underwent malignant transformation. The weighted remission rate was higher for surgical (92.8%) compared to non‐surgical treatment (65.9%). The recurrence rate was lower for surgical (8.4%) compared to non‐surgical treatment (19.2%). Conclusion In this systematic review, the surgical treatment was more favorable than non‐surgical for AC . Meanwhile, further studies are needed that should maximize methodological standardization and have greater rigor of the data collection process.
机译:摘要目的这一系统评价的目的是在外科杂质炎(AC)的外科和非手术治疗之间进行比较。基于系统评价和META分析指南的首选报告项目,材料和方法进行了系统审查和元分析。搜索PubMed / Medline,科学网站和Cochrane图书馆数据库。基于纳入标准选择文章:随机临床试验,前瞻性/回顾性研究和至少10名患者的病例系列,最低随访时间为6个月。进行加权缓解率(RER)和复发率(RR),具有95%置信区间。使用全面的Meta-Analysis软件进行数据分析。结果包括10项研究总共283个AC S。约2.5%的手术治疗病例接受恶性转化。与非手术治疗相比,手术(92.8%)的加入缓解率较高(65.9%)。与非手术治疗相比,手术(8.4%)的复发率降低(19.2%)。结论在该系统审查中,外科治疗比非外科对AC的含量更有利。同时,需要进一步的研究,即最大化方法标准化并具有更大的数据收集过程严谨。

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