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首页> 外文期刊>Scandinavian journal of medicine & science in sports. >Effects of exercising before breakfast on the health of T2DM patients—A randomized controlled trial
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Effects of exercising before breakfast on the health of T2DM patients—A randomized controlled trial

机译：早餐前锻炼对T2DM患者健康的影响 - 一种随机对照试验

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This is the first study to examine whether training before breakfast in the overnight‐fasted state is more effective in improving the health of patients with type 2 diabetes mellitus (T2DM) than after breakfast in the fed state. Thirty T2DM patients ( 60?±?8?years, 33.7?±?4.6?kg/m 2 ) were randomly assigned to the F group (training in the overnight‐fasted state (n?=?15)) and to the C group (training in the fed state (control group, n?=?15)). All patients completed an 8‐week combined endurance/strength training program. Physical training significantly increased time to physical exhaustion during an endurance test (+10.4%), power output during strength tests (chest presses: +36.7% and seated rows: +37.8%), and fat‐free mass (+1.7?kg). Body fat mass (?1.9?kg), glycated hemoglobin (HbA1c) values (absolute change: ?0.3%), serum insulin values (?2.5?microU/mL), the homeostatic model assessment for insulin resistance (HOMA‐IR) index (?1.1), and circulating triglyceride levels (?31?mg/dL) decreased significantly from pre‐ to post‐training. The training had no effect on body mass index, serum fasting glucose, total cholesterol, low‐density lipoprotein/high‐density lipoprotein ratio or interleukin (IL)‐6, IL‐10 and tumor necrosis factor (TNF)α levels. Analyses of variance revealed no time?×?group interaction for any variable ( P ??.05). The training was effective in improving the health of T2DM patients. However, the preliminary study's data do not provide any evidence that the nutritional state (overnight‐fasted or fed) in regular physical training plays a significant role for training‐induced adaptations in T2DM patients. Full trials (using other training protocols as well) should be conducted to gain further knowledge about the relevance of pre‐exercise breakfast ingestion.
机译：这是第一次研究在过夜禁食状态下早餐前培训是否更有效地改善2型糖尿病患者（T2DM）的健康，而不是在美联储状态下早餐。三十台D2DM患者（60？±8？岁，33.7？±4.6？kg / m 2）被随机分配给F组（在过夜禁食状态下训练（n？=？15））和c小组（在美联储培训（对照组，N？=？15））。所有患者完成了8周的综合耐力/强度培训计划。身体训练在耐久性测试期间的身体耗尽显着增加（+ 10.4％），力量试验期间的功率输出（胸部压力机：+ 36.7％和坐行：+ 37.8％）和无脂肪质量（+1.7？kg） 。体脂肪质量（α1.9？kg），糖化血红蛋白（Hba1c）值（绝对变化：α0.3％），血清胰岛素值（？2.5？microu / ml），胰岛素抵抗的稳态模型评估（homa-ir）指数（？1.1），并且循环甘油三酯水平（αmg/ dl）从预训练后显着降低。培训对体重指数，血清禁食葡萄糖，总胆固醇，低密度脂蛋白/高密度脂蛋白比例或白细胞介素（IL）-6，IL-10和肿瘤坏死因子（TNF）α水平没有影响。差异的分析显示出没有时间？×？α？群体的任何变量的相互作用（p？＆？05）。培训在改善T2DM患者的健康方面有效。然而，初步研究的数据没有提供任何证据表明常规体育训练中的营养状态（过夜或喂养）在T2DM患者中培训诱导的适应发挥着重要作用。应进行全面试验（也使用其他培训协议），应进一步了解锻炼前早餐摄取的相关性。

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