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首页> 外文期刊>Seminars in Diagnostic Pathology >Primary cutaneous B-cell lymphomas with large cell predominance primary cutaneous follicle center lymphoma, diffuse large B-cell lymphoma, leg type and intravascular large B-cell lymphoma
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Primary cutaneous B-cell lymphomas with large cell predominance primary cutaneous follicle center lymphoma, diffuse large B-cell lymphoma, leg type and intravascular large B-cell lymphoma

机译：主要皮肤B细胞淋巴瘤，具有大细胞主要皮肤卵泡中心淋巴瘤，弥漫性大B细胞淋巴瘤，腿型和血管内大B细胞淋巴瘤

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摘要

In this review, we present clinical features and detailed histopathologic, immunologic, and molecular information regarding primary cutaneous follicle center lymphoma and primary cutaneous diffuse large B-cell lymphoma, leg type which together represent two of the three most common types of primary cutaneous B-cell lymphoma recognized in the current WHO classification system.(1,2) Overall, B-cell lymphomas represent 19-27% of primary cutaneous lymphomas in most large European and American studies(3-6) and together, primary cutaneous follicle center lymphoma and primary cutaneous diffuse large B-cell lymphoma, leg type account for approximately 2/3 to 3/4 of these cases.(5,7-11) Both subtypes can contain a high content of large B-lymphocytes, although most cases of primary cutaneous follicle center lymphomas exhibit a range in cell size and cytology. Intravascular large B-cell lymphoma, a less commonly -encountered EBV-negative primary cutaneous B-cell lymphoma composed of large cells, will be more briefly discussed in this report as well. (C) 2017 Published by Elsevier Inc.
机译：在本文中，我们呈现临床特征和详细的组织病理学，免疫学和分子信息，关于初级皮肤卵泡中心淋巴瘤和初级皮肤漫射大B细胞淋巴瘤，腿部代表三种最常见类型的主要皮肤B-中的两个细胞淋巴瘤在当前的分类系统中公认。（1,2）总体而言，B细胞淋巴瘤在大多数大型欧美研究（3-6）和一起，主要皮肤卵泡中心淋巴瘤和初级皮肤弥漫性大B细胞淋巴瘤，腿型占这些病例的约2/3至3/4。（5,7-11）两种亚型可含有高含量的大B淋巴细胞，尽管大多数情况下主要皮肤卵泡中心淋巴瘤在细胞大小和细胞学中表现出范围。血管内大的B细胞淋巴瘤，在本报告中更简单地讨论了由大细胞组成的较少常见的EBV阴性初级皮肤B细胞淋巴瘤。 （c）2017年由elsevier公司发布

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