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首页> 外文期刊>ORL: Journal for oto-rhino-laryngology and its borderlands >Mucoepidermoid Carcinoma of the Parotid: Very Close Margins and Adjuvant Radiotherapy
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Mucoepidermoid Carcinoma of the Parotid: Very Close Margins and Adjuvant Radiotherapy

机译：腮腺蛋白癌癌的腮腺癌：非常紧密的边缘和佐剂放射治疗

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Background/Aims: The importance of adjuvant radiotherapy in patients with close margin resections for mucoepidermoid carcinoma of the parotid gland remains unclear. Methods: Patients who underwent parotidectomy for mucoepidermoid carcinoma with or without adjuvant radiotherapy at a single academic tertiary care center from 2000 to 2014 were identified. Included patients had negative but close (<= 2 mm) surgical margins without other high-risk histopathological factors including advanced T-stage, positive nodal disease, lymphovascular or perineural invasion, or high-grade histology. Results: Nineteen patients were identified, of whom 15 (79%) were observed postoperatively, while 4 (21%) underwent adjuvant radiotherapy. There were no significant differences in extent of parotidectomy, elective neck dissection, T staging, or tumor size between patients who were observed and those undergoing adjuvant radiation. There were no locoregional or distant recurrences in any patients at a mean follow up 74.3 months. Patients undergoing adjuvant radiation, however, had significantly more intermediate-grade as compared to low-grade histology (75% vs. 13%, difference 62%, 95% CI 4% to 100%). Conclusions: Patients with negative but close (<= 2 mm) surgical margins without other high-risk histopathological factors have excellent long-term locoregional control with surgery alone. The effects of adjuvant radiotherapy for those who have intermediate-grade disease remain uncertain. (C) 2019 S. Karger AG, Basel
机译：背景/宗旨：辅助放射治疗在腮腺粘膜皮肤癌癌的近距离切除患者中的重要性仍不清楚。方法：鉴定了从2000年至2014年从2000年至2014年的单一学术三级护理中心进行或不带佐剂放射治疗的粘液切感术治疗药物切割术的患者。包括患者的患者具有消极但关闭（<= 2mm）手术边缘，没有其他高风险的组织病理因素，包括晚期T-阶段，阳性节点疾病，淋巴血管或危及侵袭，或高等级组织学。结果：术后鉴定了19名患者，其中术后4例（79％），而4（21％）接受佐剂放射治疗。观察到的患者之间的腮腺切除术，选修颈切除术的程度没有显着差异，T分期，T分期和肿瘤大小以及经历佐剂辐射的患者。任何患者都没有患者在均值74.3个月内没有招待或遥远的再次发生。然而，与低级组织学相比，经历辅助辐射的患者具有显着更高的中间级（75％对13％，差异62％，95％CI 4％至100％）。结论：负且近乎闭合（<= 2mm）的患者，没有其他高风险的组织病理因素的手术边缘具有优异的长期招诊所，单独使用手术进行手术。佐剂放射治疗对那些具有中等级疾病的人的影响仍然不确定。 （c）2019年S. Karger AG，巴塞尔

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