...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ORL: Journal for oto-rhino-laryngology and its borderlands >Preoperative Serum Thyroglobulin Level as a Useful Predictive Marker to Differentiate Thyroid Cancer
【24h】

Preoperative Serum Thyroglobulin Level as a Useful Predictive Marker to Differentiate Thyroid Cancer

机译：术前血清甲状腺球蛋白水平作为分化甲状腺癌的有用预测标记物

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: Thyroid cancer is the most common endocrine system cancer. Although fine-needle aspiration biopsy is the most commonly used method for diagnosis, it is not always sufficient. The aim of this study was to investigate the influence of preoperative serum thyroglobulin (Tg) concentration on differentiated thyroid cancer risk. Material and Methods: A total of 133 patients who underwent total thyroidectomy due to various indications at the Ear-Nose-Throat Department, Ataturk University Medical School, between April 2015 and December 2015, were included in this prospective study. Histopathological diagnosis and preoperative Tg levels were compared. Receiver operating characteristic (ROC) analysis was used for detection of the cut-off to discriminate malignant from benign thyroid masses using preoperative Tg as a variable. Results: Malignant pathology (differentiated thyroid carcinoma) was detected in 59 out of 133 patients (44.4%) and benign pathology in 74 (55.6%). A statistically significant difference in preoperative Tg value was detected between malignant and benign cases (p 0.05). Conclusion: The prevalence of differentiated thyroid carcinoma was higher among patients with a preoperative serum Tg value 188.5 ng/mL, and this may thus be used as a marker for the diagnosis of this malignancy. (C) 2018 S. Karger AG, Basel
机译：介绍：甲状腺癌是最常见的内分泌系统癌症。虽然细针吸入活检是最常用的诊断方法，但它并不总是足够的。本研究的目的是探讨术前血清甲状腺素（TG）浓度对分化的甲状腺癌风险的影响。材料和方法：在2015年4月至2015年4月期间，耳鼻喉科大学医学院的各种适应症，共有133名接受甲状腺切除术的患者，于2015年4月和2015年12月，纳入了这项前瞻性研究。比较组织病理学诊断和术前TG水平。接收器操作特性（ROC）分析用于检测截止，以使用术前TG作为可变的良性甲状腺质量来区分恶性甲状腺质量。结果：在133名患者中的59名（44.4％）和74名（55.6％）中，检测到恶性病理学（分化的甲状腺癌）。在恶性和良性病例之间检测到术前TG值的统计学显着性差异（P <0.05）。结论：术前血清TG值患者中分化的甲状腺癌的患病率较高。因此，这可以用作诊断这种恶性肿瘤的标志物。 （c）2018年S. Karger AG，巴塞尔

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号