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首页> 外文期刊>Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer >Clinical and psychometric validation of the BreSAS questionnaire module for symptom assessment among breast cancer survivors
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Clinical and psychometric validation of the BreSAS questionnaire module for symptom assessment among breast cancer survivors

机译：乳腺癌幸存者症状评估的临床和心理测量验证

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Background The large number of women surviving many years post breast cancer (BC) diagnosis has heightened interest in studying long-term effects of cancer on quality of life (QoL). Several cancer-specific health-related measures have been developed, but these may not be appropriate for long survivors. This study evaluates the reliability and clinical and psychometric validity of the BreSAS questionnaire (BQ) among BC survivors. Methods The BQ is a quick, simple ten-item module for the assessment of long-term physical, psychological, sexual, and cognitive effects that may influence QoL. The total BreSAS score ranks from 0 to 100, with a low score indicating a better QoL. Patients complete the BQ, the FACT-ES questionnaire, and case report forms for clinical and socio-demographic data during follow-up visits. Reliability and clinical and psychometric validity of the questionnaires are assessed by correlation analyses and exploration of known group comparisons. Results From September 2015 to February 2016, 149 patients from three Italian oncology units were enrolled. Baseline questionnaires were returned from all, and 134 patients (89%) completed the BQ and FACT-ES in less than 15 min. For reliability, Cronbach's alpha coefficients for each scale were greater than 0.70 in all analyzed symptoms. Convergent validity of BQ showed by Pearson's r demonstrated a high correlation between intensity of symptoms and QoL, especially for pain and depression. No data were provided about reproducibility with test-retest study. Conclusion The BQ demonstrates sufficient validity and reliability to support its use to assess patient-reported symptoms during planned follow-up clinical visits among BC survivors. Further full validation studies are needed.
机译：背景技术许多妇女在乳腺癌（BC）诊断后患有多年的患者，对癌症的长期影响提高了对癌症的长期影响（QOL）的兴趣。已经制定了几种癌症特异性健康有关的措施，但这些措施可能不适合长幸存者。本研究评估了BC幸存者中BRESAS问卷（BQ）的可靠性和临床和心理测量有效性。方法BQ是一种快速，简单的十项模块，用于评估可能影响QoL的长期物理，心理，性，性和认知效果。总BESAS分数从0到100排名，具有低分，指示更好的QOL。患者在后续访问期间完成BQ，事实-ES问卷调查问卷和案例报告表格，以及社会人口统计数据。通过相关分析评估问卷的可靠性和临床和心理有效性，并探索已知的群体比较。结果2015年9月至2016年2月，来自三个意大利肿瘤学单位的149名患者。从所有人返回基线问卷，134名患者（89％）在不到15分钟的时间内完成BQ和FACT-ES。对于可靠性，所有分析的症状，每个刻度的Cronbach的alpha系数大于0.70。 Pearson的R显示的BQ的收敛有效性在症状和QOL强度之间表现出高的相关性，特别是对于疼痛和抑郁症。没有提供关于测试重新测试的重现性的数据。结论BQ展示了足够的有效性和可靠性，以支持其用于评估患者报告的BC幸存者中计划的后续临床访问期间的患者报告的症状。需要进一步的完整验证研究。

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