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首页> 外文期刊>Surgical pathology clinics >Cervical Glandular Neoplasia-Classification and Staging
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Cervical Glandular Neoplasia-Classification and Staging

机译：宫颈腺瘤 - 分类和分期

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摘要

Endocervical adenocarcinomas (EAs) account for 25% of all primary cervical carcinomas. Approximately 85% of EAs are driven by high-risk human papillomavirus (HPV) infection, the most common of which is the so-called usual type endocervical adenocarcinomas. Non-HPV-driven subtypes harbor distinct clinicopathologic features and prognosis and have been increasingly recognized in recent years, which has led to efforts to improve classification of EA based on clinically relevant and reproducible criteria. This review discusses a recently proposed classification system, the International Endocervical Adenocarcinoma Criteria and Classification, which uniquely integrates morphology, cause/pathogen-esis, and biological behavior of HPV and non-HPV-driven subtypes of EA.
机译：内膜腺癌（EAS）占所有原发性宫颈癌的25％。 大约85％的EA中由高风险的人乳头瘤病毒（HPV）感染驱动，最常见的是所谓的通常类型的内膜腺癌腺癌。 非HPV驱动的亚型含有不同的临床病理特征和预后，并且近年来越来越认识到，这导致基于临床相关和可重复标准来改善EA的分类。 本综述讨论了最近提出的分类系统，国际内科腺癌腺癌标准和分类，其唯一地整合了HPV和非HPV驱动亚型的形态，原因/病原体 - IER和生物学行为。

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