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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Early Factors Associated with the Development of Chronic Pain in Trauma Patients
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Early Factors Associated with the Development of Chronic Pain in Trauma Patients

机译：与创伤患者慢性疼痛的发展相关的早期因素

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Objective. To identify factors, available at the time of trauma admission, associated with the development of chronic pain to allow testing of preventive approaches. Methods. In a retrospective observational cohort study, we included all patients?≥?18 years old admitted for injury in 57 adult trauma centers in the province of Quebec (Canada) between 2004 and 2014. Chronic pain was defined as follows: treated in a chronic pain clinic, diagnosed with chronic pain, or received at least 2 prescriptions of chronic pain medications 3 to 12 months postinjury. Results. A total of 95,134 patients were retained for analysis. Mean age was 59.8 years (±21.7), and 52% were men. The causes of trauma were falls (63%) and motor vehicle accidents (22%). We identified 14,518 patients (15.3%; 95% CI: 15.1–15.5) who developed chronic pain. After controlling for confounding factors, the variables associated with chronic pain were spinal cord injury (OR?=?3.9; 95% CI: 3.4–4.6), disc-vertebra trauma (OR?=?1.6; 95% CI: 1.5–1.7), history of alcoholism (OR?=?1.4; 95% CI: 1.2–1.7), history of anxiety (OR?=?1.4; 95% CI: 1.2–1.5), history of depression (OR?=?1.3; 95% CI: 1.1–1.4), and being female (OR?=?1.3; 95% CI: 1.2–1.3). The area under the receiving operating characteristic curve derived from the model was 0.80. Conclusions. We identified risk factors present on hospital admission that can predict trauma patients who will develop chronic pain. These factors should be prospectively validated.
机译：客观的。为了识别创伤入院时可用的因素，与慢性疼痛的发展有关，以允许测试预防方法。方法。在回顾性观察队列研究中，我们包括所有患者？≥18岁，在2004年至2014年魁北克（加拿大）省内57个成人创伤中心受伤入院。慢性疼痛定义如下：慢性疼痛治疗诊断患有慢性疼痛的诊所，或至少2个慢性疼痛药物预科3至12个月的慢性疼痛药物。结果。保留了95,134名患者进行分析。平均年龄为59.8岁（±21.7），52％是男性。创伤的原因是下降（63％）和机动车辆事故（22％）。我们确定了14,518名患者（15.3％; 95％CI：15.1-15.5），他开发了慢性疼痛。在控制混淆因素后，与慢性疼痛相关的变量是脊髓损伤（或？= 3.9; 95％CI：3.4-4.6），椎间盘突出（或？=？1.6; 95％CI：1.5-1.7 ），酗酒的历史（或？=？1.4; 95％CI：1.2-1.7），焦虑史（或？=？1.4; 95％CI：1.2-1.5），抑郁史（或？=？1.3; 95％CI：1.1-1.4），是女性（或？=？1.3; 95％CI：1.2-1.3）。来自模型的接收操作特性曲线下的区域为0.80。结论。我们确定了医院入院的风险因素，可预测会产生慢性疼痛的创伤患者。这些因素应该是前瞻性的验证。

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