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首页> 外文期刊>Pain medicine : >Efficacy and Safety of Extracorporeal Shockwave Therapy for Treatment of Knee Osteoarthritis: A Systematic Review and Meta-analysis
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Efficacy and Safety of Extracorporeal Shockwave Therapy for Treatment of Knee Osteoarthritis: A Systematic Review and Meta-analysis

机译：体外冲击波治疗治疗膝关节骨关节炎的功效和安全性：系统评价和荟萃分析

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Objective. The objective of this study was to assess the efficacy and safety of extracorporeal shockwave therapy (ESWT) for treatment of knee osteoarthritis (OA) using a systemic review and meta-analysis. Methods. An extensive search of relevant articles from electronic databases Pubmed, Embase, and Cochrane Library from inception to March 2019 was conducted. The treatment outcomes (visual analog scale [VAS] and the Western Ontario and McMaster Universities Arthritis Index [WOMAC]) of the included articles were pooled to calculate effect sizes. The assessment of heterogeneity among articles was evaluated using I-2. Statistical analyses were conducted using RevMan software. Results. The results showed that the ESWT group had significant improvement in pain relief compared with the control group through 12 months based on WOMAC and VAS scores. Compared with the baseline level, the patients had significant improvement in pain relief at most follow-up points (one week to 12 months) based on WOMAC and VAS scores. The patients showed significant improvement in physical function at six- and 12-month follow-up when compared with the control group and for all follow-up (one to 12 months) when compared with the baseline level. Additionally, only minor complications were observed after ESWT treatment. Conclusions. The use of ESWT for treatment of knee OA had a beneficial effect on pain relief and physical function improvement for up to 12 months, and only minor complications occurred after ESWT treatment. However, there remains a lack of clarity regarding the frequency and dosage levels of ESWT required to achieve the maximum improvement.
机译：客观的。本研究的目的是评估使用全身审查和荟萃分析来评估体外冲击波治疗（ESWT）的疗效和安全性治疗膝关节骨关节炎（OA）。方法。在2019年3月，进行了广泛地搜索了电子数据库中的相关文章，从2009年到2019年3月到2019年3月的Cochrane图书馆。汇集了治疗结果（视觉模拟[VAS]和Western Ontario和麦克马斯特大学关节炎指数[Womac]）被汇总以计算效果大小。使用I-2评估制品之间的异质性的评估。使用Revman软件进行统计分析。结果。结果表明，与对照组到基于WOMAC和VAS分数的12个月相比，ESWT组对疼痛缓解具有显着改善。与基线水平相比，基于Womac和VAS分数的大多数后续点（一周至12个月），患者对疼痛缓解的显着改善。与基线水平相比，患者在与对照组和所有随访相比时，六个月和12个月的随访表现出显着改善。此外，在ESWT治疗后只观察到次要的并发症。结论。使用ESWT用于治疗膝关节OA对疼痛缓解和物理功能改善的有益影响长达12个月，只有在ESWT治疗后发生的轻微并发症。然而，仍然缺乏关于达到最大改善所需的ESWT的频率和剂量水平的清晰度。

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