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Foundation of pediatric cancer treatment in Lao People's Democratic Republic at the Lao-Korea National Children's Hospital

机译:老挝人民民主共和国在老挝民族儿童医院的小儿癌治疗基础

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Aim: The Lao-Korea National Children's Hospital initiated and developed a pediatric cancer treatment program for the first time in September 2012, through education by the Lee Jong-Wook project, establishment of infrastructure by the Korea International Cooperation Agency, and cooperation of medical staff.Material and Methods: we describe the experience of initiating and building this program by retrospectively reviewing the data from pediatric patients with cancer diagnosed at the Lao-Korea National Children's Hospital between September 2012 and December 2016.Results: A total of 78 patients diagnosed with acute lymphoblastic leukemia (ALL) (n=44), acute myeloid leukemia (AML) (n=12), chronic myeloid leukemia (n=7), lymphoma (n=6), retinoblastoma (n=5), Wilms tumor (n=3), and germ cell tumor (n=1) were included. Of the 44 patients with ALL, 40 received induction chemotherapy, and 4 refused chemotherapy. Of these 40 patients, 29 (73.6%) achieved complete remission (CR) and 9 (22.5%) died during chemotherapy. Of the 29 patients with CR, 4 completed the chemotherapy, 19 were still on chemotherapy, 4 relapsed, and 2 were deceased. Treatment was unsuccessful for all 12 patients with AML.Conclusion: We successfully initiated the pediatric cancer care program but faced challenges associated with high mortality because of insufficient resources. We should continue our efforts to find more abandoned patients, detect cancer earlier, and reduce the overall associated mortality.
机译:目的:老挝国家儿童医院于2012年9月首次启动和开发了儿科癌症治疗方案,通过李继辉项目,由韩国国际合作机构建立基础设施,以及医务人员的合作。材料和方法:我们通过回顾性地审查2012年9月至2016年9月至2016年12月至12月在老挝国民医院诊断癌症中的儿科患者的数据来描述启动和建立本计划的经验。结果:共有78例诊断患者急性淋巴细胞白血病(ALL)(n = 44),急性髓性白血病(AML)(n = 12),慢性髓性白血病(n = 7),淋巴瘤(n = 6),视网膜母细胞瘤(n = 5),WILMS肿瘤( n = 3),包括生殖细胞肿瘤(n = 1)。在44名患者中,40名接受的诱导化疗和4例拒绝化疗。在这40例患者中,29例(73.6%)在化疗期间取得完全缓解(Cr)和9(22.5%)。在29例CR,4患者中完成化疗,19例仍在化疗上,4次复发,2分复活响。所有12例AML的治疗都没有成功。结论:我们成功启动了儿科癌症治疗计划,但由于资源不足,患有高死亡率的面临挑战。我们应该继续努力寻找更遗弃的患者,仔细检测癌症,并降低整体的相关死亡率。

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