...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Poultry Science >Molecular characteristics of avian leukosis viruses isolated from indigenous chicken breeds in China
【24h】

Molecular characteristics of avian leukosis viruses isolated from indigenous chicken breeds in China

机译：中国土着鸡品种中分离的禽白血病病毒的分子特征

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To assess the status of avian leukosis virus (ALV) infection in indigenous chicken breeds in China, 121 plasma samples collected from various indigenous chicken breeds were tested for the presence of ALV from 2015 to 2016. A total of 14 ALV strains were isolated and identified, including two ALV-A strains, one ALV-B strain, eight ALV-J strains, and three ALV-K strains. To study the genome structure, biological characteristics, and the evolutionary relationships of the ALV-K strains with other known subgroup strains from infected chickens, we determined the complete genome sequence of the three ALV-K strains and performed comparative analysis using the whole genome sequence or selected sequence elements. The replication rates of the three ALV-K strains were markedly lower than the rates of other ALVs, and they shared a common mutation in the pol gene, which had not been previously observed. In addition, nine putative recombinant events were detected in the genomes of the three newly isolated ALV-K strains, with high statistical support. This was the first report of an ALV-K re-organization event, which has contributed to its genetic evolution. In summary, we established a robust classification system for ALV, especially for ALV-K, and revealed additional genomic diversity for the ALV strains in indigenous chicken breeds. Therefore additional works are warranted to explore ALV genomics and epidemiology.
机译：为了评估中国土着鸡品种中的禽白血病病毒（ALV）感染的状态，从2015至2016年从各种土着鸡品种中收集的121个血浆样本进行了50〜2016年。分离并鉴定了总共14个ALV菌株，包括两种Alv-A菌株，一种Alv-B株，8 Alv-J菌株和三种Alv-K菌株。为了研究基因组结构，生物学特性和Alv-k菌株与来自受感染的鸡的其他已知的亚组菌株的进化关系，我们确定了三种Alv-k菌株的完整基因组序列并使用全基因组序列进行比较分析或选择的序列元素。三种Alv-K菌株的复制率明显低于其他ALV的速率，并且它们在POL基因中分享常见的突变，这尚未观察到。此外，在三种新分离的Alv-K菌株的基因组中检测到九种推定的重组事件，具有高统计载体。这是ALV-K重新组织事件的第一份报告，这为其遗传演变做出了贡献。总之，我们为ALV建立了稳健的分类系统，特别是对于ALV-K，并且揭示了土着鸡品种中ALV菌株的额外基因组多样性。因此，有必要额外的作品来探索ALV基因组学和流行病学。

著录项

  • 来源
    《Poultry Science》 |2018年第8期|共9页
  • 作者

    Su Qi; Li Yang; Li Weihua; Cui Shuai; Tian Sibao; Cui Zhizhong; Zhao Peng; Chang Shuang;

  • 作者单位

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

    China Anim Hlth &

    Epidemiol Ctr Qingdao 266032 Peoples R China;

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

    Shandong Agr Univ Shandong Prov Key Lab Anim Biotechnol &

    Dis Contr Shandong Prov Engn Technol Res Ctr Anim Dis Contr Coll Vet Med Tai An 271018 Shandong Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 畜牧、动物医学、狩猎、蚕、蜂;
  • 关键词

    avian leukosis virus; indigenous chicken breed; recombinant; genetic evolution; mutation;

    机译：禽类白血病病毒;土着鸡养殖;重组;遗传演化;突变;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号