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首页> 外文期刊>BJU international >Metabolic characteristics of the elderly with recurrent calcium oxalate stones.
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Metabolic characteristics of the elderly with recurrent calcium oxalate stones.

机译：老年人草酸钙结石的代谢特征。

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摘要

OBJECTIVE: To determine the metabolic characteristics of elderly patients with recurrent calcium oxalate stones. PATIENTS AND METHODS: Metabolic abnormalities were investigated in 88 patients with recurrent calcium oxalate stones, including 70 aged <60 years and 18 aged >/=60 years. The frequency of each metabolic abnormality and the value of each urinary constituent were compared among subgroups of age and gender. RESULTS: Hyperoxaluria was the most common abnormality, present in 56% and 67% of patients aged <60 and >/=60 years, respectively. Hyperuricosuria was significantly more common in older than in younger patients. There were no significant differences in the frequencies of hypercalciuria and hypocitraturia between the age groups. The urinary excretion of oxalate and the ratio of oxalate to creatinine were significantly greater in older than in younger men. The frequency of low urine volume was lower in older than in younger patients and the mean urinary volume was also greater in the older group. CONCLUSIONS: Hyperuricosuria and hyperoxaluria seem to be essential risk factors for calcium oxalate stone formation in elderly patients. Urinary oxalate excretion is significantly greater in older than in younger stone formers and is more prominent in men.
机译：目的：确定老年草酸钙结石患者的代谢特征。病人和方法：对88例复发性草酸钙结石患者的代谢异常进行了调查，其中包括70岁<60岁和18岁> / = 60岁。在年龄和性别的亚组中比较了每种代谢异常的频率和每种尿液成分的价值。结果：高草酸尿症是最常见的异常，<60岁和> / = 60岁的患者分别占56％和67％。高尿酸尿症在老年人中比在年轻患者中更为普遍。在不同年龄组之间，高钙尿症和低尿酸的发生频率没有显着差异。草酸盐的尿排泄量和草酸盐与肌酐的比率明显大于年轻男子。老年患者的低尿量发生率低于年轻患者，老年患者的平均尿量也较大。结论：尿酸尿过多和高草酸尿症似乎是老年患者草酸钙结石形成的重要危险因素。老年人中草酸尿的排泄量明显大于年轻的结石患者，并且在男性中更为明显。

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