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Identifying Moderators of Response to the Penn Resiliency Program: A Synthesis Study

机译:识别对宾夕法尼亚州弹性计划的主持人:合成研究

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Abstract To identify moderators of a cognitive-behavioral depression prevention program’s effect on depressive symptoms among youth in early adolescence, data from three randomized controlled trials of the Penn Resiliency Program (PRP) were aggregated to maximize statistical power and sample diversity ( N ?=?1145). Depressive symptoms, measured with the Children’s Depression Inventory (CDI; Kovacs 1992), were assessed at six common time points over two-years of follow-up. Latent growth curve models evaluated whether PRP and control conditions differed in the rate of change in CDI and whether youth- and family-level characteristics moderated intervention effects. Model-based recursive partitioning was used as a supplementary analysis for identifying moderators. There was a three-way interaction of PRP, initial symptom severity, and intervention site on growth in depressive symptoms. There was considerable variability in PRP’s effects, with the nature of the interaction between PRP and initial symptom levels differing considerably across sites. PRP reduced depressive symptoms among youth with unmarried parents, but not among those with married parents. Finally, PRP’s effects differed across school grade levels. Although initial symptom severity moderated PRP’s effect on depressive symptoms, it was not a reliable indicator of how well the intervention performed, limiting its utility as a prescriptive variable. Our primary analyses suggest that PRP’s effects are limited to youth whose parents are unmarried. The small number of fifth grade students ( n ?=?25; 2?%) showed a delayed and sustained intervention response. Our findings underscore the importance of evaluating site, family, and contextual characteristics as moderators in future studies.
机译:摘要为了鉴定认知行为抑郁症预防计划的主持人对青年青春期中青年中的抑郁症状的影响,聚集了来自钢笔弹性计划(PRP)的三次随机对照试验的数据,以最大化统计功率和样本多样性(n?=? 1145)。与儿童抑郁库存(CDI; Kovacs 1992)测量的抑郁症状,在两年后的六个常见时间点评估。潜在的生长曲线模型评估了PRP和控制条件是否与CDI的变化率不同,以及家庭级别特征是否适度的干预效果。基于模型的递归分区被用作识别主持人的补充分析。 PRP,初始症状严重程度和干预现场有三种互动性抑郁症状的增长。 PRP的效果存在相当大的变化,PRP与初始症状水平之间的相互作用的性质在横跨网站上的相当不同。与未婚父母的青年中,PRP减少了抑郁症状,但不包括已婚父母的父母。最后,PRP的效果跨学校等级不同。虽然初始症状严重程度患PRP对抑郁症状的影响,但这不是一种可靠的指标,这些指标如何进行干预的效果,限制其作为规范性变量的实用性。我们的主要分析表明,PRP的影响仅限于父母未婚的青年。少数五年级学生(n?= 25; 2?%)显示出延迟和持续的干预响应。我们的调查结果强调了在未来的研究中评估网站,家庭和语境特征作为主持人的重要性。

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