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首页> 外文期刊>Prevention science: the official journal of the Society for Prevention Research >Can We Trust Positive Findings of Intervention Research? The Role of Conflict of Interest
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Can We Trust Positive Findings of Intervention Research? The Role of Conflict of Interest

机译：我们可以信任干预研究的积极发现吗？ 利益冲突的作用

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Abstract In recent years, there has been increased attention to the issue of conflict of interest within prevention research. The aims of this paper are to discuss these developments and to relate them to discussions of conflict of interest in the broader scientific literature. Although there has been concern expressed about the extent to which conflicts of interest can be defined and measured, empirical research suggests that financial conflicts can be easily identified and assessed in meta-analyses focused on their effects on research quality. Research evidence also shows that conflict of interest is associated with use of flexible data analysis practices and the reporting of chance positive findings, both within prevention research and related disciplines such as public health and psychology. However, the overwhelming majority of published studies report positive results, and there are a number of other influences within academia (such as pressure to publish) that account for this and for the use of flexible data analysis practices. Accordingly, introducing measures to improve research quality in general, rather than just focusing on problems specific to research in which there is a clearly identifiable conflict of interest, may prove more effective and less controversial. Most such efforts focus on introducing greater transparency into research design, practice, and reporting. These both curtail employment of flexible data analysis practices and make their use transparent to investigators seeking to assess their effects on research quality. Also, requiring detailed disclosures of conflicts be reported by all investigators (not just senior authors) would improve current disclosure practices.
机译：摘要近年来，预防预防研究中利益冲突问题的关注。本文的目标是讨论这些发展，并将其与讨论更广泛的科学文学的利益冲突。虽然有关利益冲突的程度，但衡量了令人关切的是，但实证研究表明，在荟萃分析中，可以轻易识别和评估金融冲突，重点是它们对研究质量影响的荟萃分析。研究证据还表明，利益冲突与利用灵活的数据分析实践以及机会阳性发现的报告，包括在预防研究和公共卫生和心理学等相关学科中。然而，绝大多数出版的研究报告了积极的结果，并且在学术界（如发表的压力）中有许多其他影响，该占据了这一点和使用灵活的数据分析实践。因此，介绍了一般性地提高研究质量的措施，而不是专注于研究的问题，其中有明显可识别的利益冲突，可能会更有效和更有争议。大多数此类努力侧重于引入更大的透明度，进入研究设计，实践和报告。这些都削减了灵活的数据分析实践的就业，并使他们对寻求评估其对研究质量影响的调查人员的透明。此外，要求所有调查人员报告的详细披露冲突（不仅仅是高级作者）将改善当前的披露行为。

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