Imatinib: muscle pain suggestive of a withdrawal syndrome

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Imatinib: muscle pain suggestive of a withdrawal syndrome

机译：imatinib：肌肉疼痛暗示戒断综合征

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Muscle pain after stopping imatinib that resolves on reintroduction of the drug. Imatinib is a tyrosine kinase inhibitor that inhibits the oncoprotein BCR-ABL. It is mainly used in various forms of acute and chronic leukaemia in adults and children (1). Imatinib's adverse effects include muscle pain, joint pain and cramps. Muscle pain after stopping imatinib is suggestive of a withdrawal syndrome (1).

机译：停止伊马替尼后肌肉疼痛，以解决药物的重新引入。伊马替尼是酪氨酸激酶抑制剂，其抑制癌蛋白BCR-ABL。它主要用于成人和儿童的各种形式的急性和慢性白血病（1）。伊马替尼的不良反应包括肌肉疼痛，关节疼痛和痉挛。停止伊马替尼后的肌肉疼痛是提示戒断综合征（1）。

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《Prescrire international》 |2016年第169期|共1页
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中图分类药学;
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1. Imatinib: muscle pain suggestive of a withdrawal syndrome [J] . Prescrire international . 2016,第169期

机译：imatinib：肌肉疼痛暗示戒断综合征
2. Musculoskeletal pain in patients with chronic myeloid leukemia after discontinuation of imatinib: A tyrosine kinase inhibitor withdrawal syndrome? [J] . RichterJ., S?derlundS., LübkingA., Journal of Clinical Oncology . 2014,第25期

机译：伊马替尼停药后慢性骨髓性白血病患者的肌肉骨骼疼痛：酪氨酸激酶抑制剂戒断综合征？
3. Musculoskeletal pain in patients with chronic myeloid leukemia after discontinuation of imatinib: A tyrosine kinase inhibitor withdrawal syndrome? [J] . RichterJ., S?derlundS., LübkingA., Journal of Clinical Oncology . 2014,第25期

机译：伊马替尼停药后慢性骨髓性白血病患者的肌肉骨骼疼痛：酪氨酸激酶抑制剂戒断综合征？
4. Using EMG to evaluate muscle functions in patients with low back pain (LBP) syndromes [C] . Lu, W.W., Luk, Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE . 1998

机译：使用EMG评估下腰痛（LBP）综合征患者的肌肉功能
5. The mechanistic role of pain appraisals and behavioural coping strategies between pain and quality of life in Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS). [D] . Krsmanovic, Adrijana. 2013

机译：慢性前列腺炎/慢性盆腔痛综合征（CP / CPPS）中疼痛评估和行为应对策略之间的疼痛作用和行为应对策略的作用。
6. Imatinib withdrawal syndrome and longer duration of imatinib have a close association with a lower molecular relapse after treatment discontinuation: the KID study [O] . Sung-Eun Lee, Soo Young Choi, Hye-Young Song, 2016

机译：KID研究表明伊马替尼戒断综合征和伊马替尼持续时间较长与停药后较低的分子复发密切相关
7. Imatinib withdrawal syndrome and longer duration of imatinib have a close association with a lower molecular relapse after treatment discontinuation: the KID study [O] . S.-E. Lee, S. Y. Choi, H.-Y. Song, 2016

机译：伊马替尼戒断综合征和较长的伊马替尼持续时间与治疗停止后的较低分子复发的密切关联：孩子研究

Imatinib: muscle pain suggestive of a withdrawal syndrome

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