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Biophysics and the nonlinear dynamics instigated by a special hormone

机译:精选素质和非线性动力学的生物物理学和非线性动力学

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Calcitonin, a potent hypocalcemic hormone, plays a vital role in inhibiting osteoclastic activities and suppressing bone removal. The physiological characteristics of calcitonin have long been discussed, along a few recommending calcitonin as a vestigial hormone. The basis for this article is to discuss the role of low and high levels of calcitonin in normal and osteoprotic bone turnover. The effect of calcitonin on the receptor activator of nuclear factor kappa-ligand and osteoclasts has been demonstrated using numerical simulations. This behavior recommends that treatment of osteoporosis via calcitonin does not provide the required upshots. For effectiveness calcitonin must be advised along with a combined therapy like aspirin which agrees with the experimental results available in the literature. (C) 2019 Elsevier Ltd. All rights reserved.
机译:降钙素,一种有效的低钙糖激素,在抑制骨质体活性和抑制骨移除方面起着至关重要的作用。 沿着一些推荐的降钙素作为残留激素,已经讨论了降钙素的生理特征。 本文的基础是讨论低水平降钙素在正常和骨折骨质周转中的作用。 利用数值模拟证明了降钙素对核因子Kappa-anigand和破骨细胞的受体活化剂的影响。 这种行为建议通过降钙素治疗骨质疏松症不提供所需的地板。 对于有效性降钙,必须与阿司匹林等组合疗法建议,这与文献中的实验结果一致。 (c)2019年elestvier有限公司保留所有权利。

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