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Differences in social functioning among patients with major psychiatric disorders: Interpersonal communication is impaired in patients with schizophrenia and correlates with an increase in schizotypal traits

机译:主要精神疾病患者社会功能的差异:精神分裂症患者的人际交往障碍,与斯基质型特征的增加相关

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摘要

Impaired social functioning is a hallmark of major psychiatric disorders. The purpose of this study was to detect a disorder-specific factor of social dysfunction among patients with major psychiatric disorders (PSY), including schizophrenia (SCZ), bipolar disorder (BIP) and major depressive disorder (MDD). Social functioning was assessed in patients with SCZ (n=80), BIP (n=27) or MDD (n=29) and healthy controls (HC, n=68) using the Social Functioning Scale (SFS). Compared to HC, the SCZ, BIP and MDD patient groups showed lower total SFS scores. No differences in the total scores for social functioning were observed between patient groups. We next investigated seven subscales of the SFS among PSY and observed significant diagnostic effects on all subscales of the SFS. Notably, patients with SCZ have poorer interpersonal communication than patients with MDD. Furthermore, the poorer interpersonal communication score was significantly correlated with an increase in schizotypal personality traits, as assessed by the Schizotypal Personality Questionnaire (SPQ) in HC. Although there were no differences in overall social functioning among PSY, disorder-specific factors, such as interpersonal communication, were evident in SCZ. The correlation between poor interpersonal communication and the increase in schizotypal traits suggests that poor interpersonal communication may be an intermediate phenotype of SCZ.
机译:社会功能受损是主要精神病患者的标志。本研究的目的是检测主要精神病患者(PSY)的患者社会功能障碍的疾病特异性因素,包括精神分裂症(SCZ),双相障碍(BIP)和主要抑郁症(MDD)。使用社交功能规模(SFS)对SCZ(n = 80),BIP(n = 27),BIP(n = 27)或MDD(n = 29)和健康对照(HC,N = 68)的患者进行社会功能。与HC相比,SCZ,BIP和MDD患者组显示较低的总SFS分数。在患者组之间观察到社会功能的总评分没有差异。我们接下来研究了PSY中SFS的七个分量,并观察到SFS所有类别的显着诊断效果。值得注意的是,SCZ的患者与MDD患者具有较差的人际关系通信。此外,与HC中的斯科匹卡人格问卷(SPQ)评估,较较差的人际关系通信评分与群体人格性状的增加显着相关。虽然PSY的整体社会功能没有差异,但在SCZ中是明显的,诸如人际交际等障碍特定因素。差的人际通信与斯分泌性状的增加之间的相关性表明,人际通信差可能是SCZ的中间表型。

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