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Functional connectivity of emotional well-being: Overconnectivity between default and attentional networks is associated with attitudes of anger and aggression

机译:情绪幸福的功能连接:默认和注意网络之间的过度连接与愤怒和侵略的态度相关

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Functional MRI connectivity has identified neurophysiology relevant to cognition and personality, motivating a search for relationships between brain architecture and emotional health and well-being. Two approaches were used to asses functional connectivity correlates of emotional health and well-being. The first approach used principal component analysis to evaluate resting-state functional magnetic resonance imaging data from the Human Connectome Project 1200 Subjects Data Release. Pairwise functional connectivity measurements were obtained from a 5 mm resolution parcellation of brain gray matter. Principal components were calculated for each individual and for group mean connectivity data and compared to obtain an estimate of typicality of functional connectivity for each component in each subject. Typicality scores were compared to reported emotional health metrics using a general linear model. The second approach calculated functional connectivity between each pair of networks from a 17-resting-state network cortical parcellation. Typicality of connectivity showed significant correlation across the population to emotional metrics corresponding to attitudes of anger and aggression in 3 of 10 principal components. Additionally, functional connectivity between the default and attentional networks was positively correlated with scores of attitudes of anger and aggression. These findings are consistent with a mechanism of impaired effortful control and decreased response inhibition of impulsivity.
机译:功能性MRI连接鉴定了与认知和个性相关的神经生理学,激励着寻找大脑建筑与情绪健康和福祉之间的关系。使用两种方法来赋予情绪健康和福祉的功能连接相关性。第一方法使用主成分分析来评估来自人类连接项目1200受试者数据释放的休息状态功能磁共振成像数据。从脑灰质的5mm分辨率局部获得成对功能连接测量。针对每个单独的组分和组分组的主要成分,并进行比较,以获得每个受试者中每个组分的功能连通性的典型性的估计。将典型的评分与使用一般线性模型报告的情绪健康指标进行比较。第二种方法计算来自17静态网络皮质局的每对网络之间的功能连接。连通性的典型性表明,对应于10个主要成分中3个的愤怒和侵略态度的情绪指标的显着相关性。此外,默认和注意力网络之间的功能连接与愤怒和侵略的态度的分数正相关。这些调查结果与受损的危害控制的机制一致,并降低对冲动的反应抑制。

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