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Hypertensive Disorders of Pregnancy and Symptoms of Depression and Anxiety as Related to Gestational Age at Birth: Findings From the All Our Families Study

机译:患有妊娠和焦虑症状的高血压障碍与出生时年龄相关的抑郁和焦虑:来自所有家庭的研究结果

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Objective The aim of the study was to investigate whether symptoms of depression or state anxiety changed the strength or nature of the association between hypertensive disorders of pregnancy (HDP) and gestational age at birth. Methods We conducted a secondary analysis of data from the All Our Families Cohort, a prospective pregnancy cohort study based in Calgary, Alberta, Canada. Self-reported depressive symptoms and state anxiety were assessed between 3 and 5 months of gestation, and obstetrical information, including diagnosis of HDP, parity, type of delivery, and gestational age at birth, was retrieved from the maternal discharge abstract. All models were adjusted for sociodemographic and obstetric confounders. Results Of 2763 women who had a singleton pregnancy and live birth, 247 (9%) were diagnosed with HDP. Women with HDP had significantly shorter gestational length relative to those without the diagnosis (M = 37.87 versus M = 38.99 weeks of gestation), t(2761) = 9.43, p < .001. Moderation analyses showed significant HDP by depressive symptoms and HDP by state anxiety interactions, such that the strength of the association between HDP and gestational age at birth increased alongside greater depressive symptom and state anxiety severity. Conclusions Results suggest that depressive symptoms and state anxiety may add to the increased risk for shortened gestation associated with HDP. Women at high risk of cardiovascular complications during pregnancy may benefit from additional resources to manage symptoms of depression or anxiety.
机译:目的对该研究的目的是调查抑郁或状态焦虑的症状是否改变了妊娠期(HDP)和出生时妊娠期妊娠期和妊娠年龄之间的关联的力量或性质。方法我们对所有家庭队列的数据进行了次要分析,该股东所有的家庭队列,孕妇队,加拿大艾伯塔省艾伯塔岛的预期怀孕队列研究。在妊娠3至5个月之间评估了自我报告的抑郁症状和状态焦虑,并从孕产妇排放摘要中检索孕产量,包括诊断HDP,阶段,交付类型和胎儿的孕龄。所有型号都针对社会渗目和产科杂交。结果2763名孕妇妊娠和活产,247(9%)被诊断出HDP。 HDP的女性相对于没有诊断的人具有显着缩短的妊娠长度(M = 37.87与妊娠38.99周),T(2761)= 9.43,P <.001。抑郁症状和HDP通过状态焦虑相互作用表现出显着的HDP,使得HDP与出生时期的关联的强度随着更大的抑郁症状和状态焦虑严重程度而增加。结论结果表明,抑郁症状和状态焦虑可能会增加与HDP相关的缩短妊娠的增加风险。怀孕期间心血管并发症高危的女性可能会受益于额外的资源来管理抑郁或焦虑的症状。

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