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The Prognostic Effect of Physical Health Complaints With New Cardiac Events and Mortality in Patients With a Myocardial Infarction

机译:物理健康投诉对心肌梗死患者新心脏事件和死亡率的预后作用

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Background: Self-rated general health has been associated with worse outcome after a myocardial infarction (MI). Previously, however, concurrent depression or anxiety was not taken into account. Objective: To evaluate the effect of physical health complaints post-MI on cardiac prognosis adjusting for cardiac disease severity, depression, and anxiety. Methods: The somatic subscale of the Health Complaints Scale was administered to 424 patients with MI at 3 and 12 months post MI. Types and trajectories of health complaints were identified with latent transition analysis. The prognostic effect of Health Complaints Scale sum-score at 3 months, and of types and trajectories of health complaints on combined end points (new cardiac events and mortality) was evaluated with Cox regression. Adjustments were made for age, sex, education level, living alone, history of ML left ventricular ejection fraction, depressive symptoms, and generalized anxiety disorder. Results: Overall, 189 (44.9%) patients with MI had a cardiac event or died during a mean follow-up of 5.7 (3.1) years. In the fully adjusted model, Health Complaints Scale sum-score predicted outcome (hazard ratio [HR] = 1.02 [95% CI: 1.00-1.05]). Latent transition analysis distinguished 5 groups at 3 and 12 months characterized by (1) nol minimal complaints, (2) cardiac complaints, (3) lack of energy, (4) sleep problems, and (5) mixed health complaints, resulting in 25 transition classes. Patients with cardiac and energy complaints at 3 months HRcardiac = 1.55 [1.15-2.10] and HRenergy = 1.35 [1.00-1.81]) and those with new or persistent cardiac, energy, and mixed complaints over time had a worse prognosis (HRcardiac = 1.55 [1.112.16]2.16], HRmixed 1.71 [1.19-2.47], and HRenergy = 1.51 [1.09-2.08]). Conclusions: Physical health complaints are predictors of cardiac outcome independent from cardiac disease, depression, and anxiety. Type and trajectories of health complaints may have additional prognostic significance.
机译:背景:在心肌梗死后,自我评价的一般健康状况与较差的结果有关。然而,此前,没有考虑同时抑郁或焦虑。目的:评价mi对心脏疾病严重程度,抑郁症和焦虑的心脏预后术后MI的影响。方法:在MI后3和12个月内给予健康投诉规模的体细胞次数。通过潜在转换分析确定了健康投诉的类型和轨迹。 COX回归评估了3个月的健康投诉规模总和分数和卫生投诉的类型和轨迹的疗效评估了COX回归。调整是年龄,性别,教育水平,单独生活,ML左心室喷射分数,抑郁症状和广义焦虑症的历史。结果:总体而言,189名(44.9%)MI患者患有心脏事件或在5.7(3.1)年的平均随访期间死亡。在完全调整的模型中,健康投诉刻度总和预测结果(危险比[HR] = 1.02 [95%CI:1.00-1.05])。潜在过渡分析在3和12个月内鉴别5组,其特征在于(1)NOL最小抱怨,(2)心投诉,(3)缺乏能量,(4)睡眠问题,(5)混合健康投诉,导致25过渡课程。 3个月心脏和能量投诉的患者HRCARDIAC = 1.55 [1.15-2.10]和HRONERGY = 1.35 [1.00-1.81])和具有新的或持续的心脏,能量和混合抱怨的人的预后更差(HRCARDIAC = 1.55 [1.112.16] 2.16],HRMIXED 1.71 [1.19-2.47]和HRONERGY = 1.51 [1.09-2.08])。结论:身体健康投诉是无关的心脏病,抑郁和焦虑的心脏结果预测因子。健康投诉的类型和轨迹可能具有额外的预后意义。

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