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首页> 外文期刊>Taiwan Veterinary Journal >PLETH VARIABILITY INDEX-GUIDED FLUID THERAPY LOWERS POST-OPERATIVE LACTATE LEVELS IN DOGS UNDERGOING ELECTIVE ABDOMINAL SURGERY: A RANDOMIZED CONTROLLED TRIAL
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PLETH VARIABILITY INDEX-GUIDED FLUID THERAPY LOWERS POST-OPERATIVE LACTATE LEVELS IN DOGS UNDERGOING ELECTIVE ABDOMINAL SURGERY: A RANDOMIZED CONTROLLED TRIAL

机译：综合可变异指数导向液治疗降低了接受选修腹部手术的狗工后乳酸水平：随机对照试验

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摘要

To evaluate the hemodynamic optimization effect of pleth variability index (PVI)-guided fluid therapy during abdominal surgery on tissue perfusion, 19 client-owned dogs that underwent elective abdominal surgery were randomized into control (n=10) and PVI (n=9) groups. In the control group, perioperative fluid management was based on the 2013 AAHA/AAFP Fluid Therapy Guidelines for Dogs and Cats. In the PVI group, the fluid rate was maintained based on basic daily requirements. If PVI was higher than 15% for >5min, 3–5mL/kg of crystalloid fluid bolus was infused. The tissue perfusion indicator, lactate levels, was measured at the time of intubation, extubation, and 6, 12 and 24h postoperatively. There were no significant differences in total and average fluid infused between control and PVI groups. The control group had significantly higher lactate levels than that of the PVI group at 12h postoperatively (2.2±1.0mmol/L versus 1.1±0.6mmol/L, p=0.008) and overall postoperatively (1.8±0.8mmol/L versus 1.2±0.5mmol/L, p<0.001). The control group revealed more profound hemodilution, as indicated by significantly decreased postoperative blood urea nitrogen (BUN), creatinine, and total protein. PVI-guided fluid therapy lowers lactate levels after elective abdominal surgery in dogs. Therefore, based on the result of this study PVI may provide customized fluid therapy to improve tissue perfusion and avoid unnecessary fluid overload.
机译：为了评估患有可变性指数（PVI） - 导液疗法的血流动力学优化效果在腹部手术期间组织灌注，接受选修腹部手术的19个客户所有犬被随机化（n = 10）和PVI（n = 9）团体。在对照组中，围手术期液体管理是基于2013年AAHA / AAFP流体治疗指南的狗和猫。在PVI组中，基于基本日常要求维持流体速率。如果> 5min的PVI高于15％，则注入3-5ml / kg晶体液体液。在术后插管，拔管和6,12和24h时测量组织灌注指示剂乳酸水平。在对照和PVI组之间注入的总和流体没有显着差异。对照组在术后12小时的乳酸盐水平显着高于PVI组（2.2±1.0mmol / L，P = 0.008），整体术后（1.8±0.8mmol / L与1.2±0.5 mmol / l，p <0.001）。对照组揭示了更深刻的血液稀释，如术后血尿尿素氮（BUN），肌酐和总蛋白质显着降低。 PVI引导的液体疗法降低了狗的选修腹部手术后的乳酸水平。因此，基于该研究的结果，PVI可以提供定制的流体疗法以改善组织灌注并避免不必要的流体过载。

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  • 来源
    《Taiwan Veterinary Journal》 |2018年第1期|共8页
  • 作者

    Chun-Hsiang Hu; Tien-Huan Hsu; Kuan-Sheng Chen; Wei-Ming Lee; Hsien-Chi Wang;

  • 作者单位

    *Department of Veterinary Medicine College of Veterinary Medicine National Chung Hsing University 250-1 Kuo Kuang Road Taichung City Taiwan 40227 Taiwan;

    *Department of Veterinary Medicine College of Veterinary Medicine National Chung Hsing University 250-1 Kuo Kuang Road Taichung City Taiwan 40227 Taiwan;

    *Department of Veterinary Medicine College of Veterinary Medicine National Chung Hsing University 250-1 Kuo Kuang Road Taichung City Taiwan 40227 Taiwan;

    *Department of Veterinary Medicine College of Veterinary Medicine National Chung Hsing University 250-1 Kuo Kuang Road Taichung City Taiwan 40227 Taiwan;

    *Department of Veterinary Medicine College of Veterinary Medicine National Chung Hsing University 250-1 Kuo Kuang Road Taichung City Taiwan 40227 Taiwan;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 畜牧、动物医学、狩猎、蚕、蜂;
  • 关键词

    Lactate; Pleth variability index; Perioperative fluid therapy;

    机译：乳酸;覆盖变异性指数;围手术期液治疗;

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