首页> 外文期刊>Polymer science, Series C >Electrostatic complexes of liquid and solid liposomes with spherical polycationic brushes
【24h】

Electrostatic complexes of liquid and solid liposomes with spherical polycationic brushes

机译:用球形聚合刷的液体和固体脂质体的静电复合物

获取原文
获取原文并翻译 | 示例
           

摘要

AbstractThe complexation of anionic liposomes and polymeric microspheres with grafted polycationic chains (spherical polycationic brushes) is studied. Three types of liposomes with the same molar amount of the anionic lipid are used, namely, liquid liposomes with a high mobility of lipids within the bilayer, solid liposomes with limited lateral and transmembrane mobility of lipid molecules, and solid liposomes with embedded cholesterol. All liposomes efficiently adsorb on the surface of brushes. Upon adsorption, solid liposomes begin to “leak,” that is, to release water-soluble contents in the surrounding solution, whereas solid liposomes with the embedded cholesterol preserve their integrity. Cholesterol-containing liposomes are of interest for obtaining multiliposomal containers with encapsulated biologically active compounds, catalysts, diagnostic agents, etc.
机译:[标题>摘要 ara>研究阴离子脂质体和聚合物微球与接枝的聚阳离子链(球形泛络刷)的络合。 使用具有相同摩尔量的阴离子脂质的三种类型的脂质体,即液体脂质体,具有高血液在双层内的脂质,具有有限的侧向和血液分子迁移率的固体脂质体,以及具有嵌入胆固醇的固体脂质体。 所有脂质体都有效地吸附在刷子表面上。 在吸附时,固体脂质体开始“泄漏”,即在周围溶液中释放水溶性内容物,而固体脂质体与嵌入的胆固醇保持完整性。 含胆固醇的脂质体对于获得具有包封的生物活性化合物,催化剂,诊断剂等的多层体容器。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号