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The negative effect of perioperative red blood cell transfusion on morbidity and mortality after major abdominal operations

机译:围手术期红细胞输血对主要腹部作战后发病率和死亡率的负面影响

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BackgroundThis study aims to test associations between perioperative blood transfusion and postoperative morbidity and mortality after major abdominal operations. MethodsThe 2014 ACS NSQIP dataset was queried for all patients who underwent one of the ten major abdominal operations. Separate multivariable regression models, were developed to evaluate the independent effects of perioperative blood transfusion on morbidity and mortality. ResultsOf 48,854 patients in the study cohort, 4887 (10%) received a blood transfusion. Rates of transfusion ranged from 4% for laparoscopic gastrointestinal resection to 58% for open AAA. After adjusting for significant effects of NSQIP-estimated probabilities, transfusion was independently associated with morbidity and mortality after open AAA repair (OR?=?1.99/14.4 respectively, p?≤?0.010), esophagectomy (OR?=?2.80/3.0, p?
机译:背景本研究旨在在主要腹部作战后围手术期输血和术后发病率和死亡率之间的关联。 ProtectSthe 2014 ACS NSQIP数据集被询问所有患者接受过十大腹部运营之一的患者。开发了单独的多变量回归模型,以评估围手术期血液输血对发病率和死亡率的独立影响。 48,854名患者在研究队列中,4887(10%)接受输血。腹腔镜胃肠切除术的输血率范围为开放AAA的58%。调整NSQIP估计概率的显着效果后,输血与打开AAA修复后的发病率和死亡率与发病率和死亡率相关(分别分别为P?≤α0.010),食道切除术(或?=?2.80 / 3.0, p?<?0.001),胰腺切除术(或?=α.1.88/ 3.01,p?<0.001),肝切除术(或?=?2.82 / 5.78,p?<0.001),联乳糖(或?=?2.15 / 3.17 ,p?<0.001),小肠切除(或?=α.2.81/ 3.83,p≤≤upperse)和腹腔镜胃肠道操作(或?=Δ2.73/ 4.05,p?<0.001)。结论经受化的输血与大多数主要腹部作业后的发病率和死亡率的风险不同。

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