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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19
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Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19

机译:案例报告:与Covid-19患者在患者中使用羟氯喹相关的肝毒性

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摘要

Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe COVID-19 who, after being administered HCQ, exhibited a 10-fold increase in serum levels of transaminases, followed by a rapid decrease after HCQ was withdrawn. Considering the significantly increased use of HCQduring the COVID-19 pandemic, this case alerts us to the potential for HCQ to be associated with hepatotoxicity and the need to monitor liver function during HCQ therapy.
机译:羟基氯喹(HCQ)已被用于治疗新型冠状病毒病(Covid-19)病例。 然而,有效性的证据仍然有限,不良事件可以与其使用相关。 在这里,我们报告了具有严重Covid-19的患者的患者,在施用HCQ之后,在血清转氨酶水平上表现出10倍,然后在撤回HCQ后快速降低。 考虑到利用Covid-19大流行的显着增加,这种情况提醒我们对HCQ有关与肝毒性有关的可能性以及在HCH治疗期间监测肝功能的需要。

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