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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Early Childhood Anemia in a Birth Cohort in Coastal Kenya: Links to Infection and Nutrition
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Early Childhood Anemia in a Birth Cohort in Coastal Kenya: Links to Infection and Nutrition

机译：在沿海肯尼亚的出生队列的早期儿童贫血：感染和营养的联系

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摘要

Anemia is known to impact a child's growth and development, but not all anemias are caused by iron deficiency, and the CDC and WHO have emphasized investigating other contributors to anemia. This cross-sectional sub-study of a 2012-2016 maternal-child cohort in coastal Kenya evaluated 244 children and found 185 (76%) to have been anemic on at least one time point since birth. At the time of assessment in 2016, evaluation included a complete blood count, nutritional assessment, and testing for parasitic infections, focusing on the primary outcome of anemia, defined as hemoglobin (Hb) < 11 g/dL. The average age at assessment was 20.5 +/- 7 months. Ninety-five percent had a lifetime average Hb in the anemic range. Adjusting for age and gender, prior or current malaria infection (prior: Hb beta = -0.99, 95% CI: -1.49 to -0.49, P = 0.01), or having any current infection with hookworm, Trichuris, Strongyloides, Ascaris, and/or malaria (beta = -0.84, 95% CI: -1.36 to -0.33, P = 0.01) was associated with decreased current Hb. Nutritional evaluation revealed that children with a declining Hb ate fewer vitamin-A-rich vegetables per week (P = 0.01) or eggs (P = 0.01), drank more milk (P = 0.07), and ate more bread (P = 0.01), and were more likely to live in a household that experienced food shortage (P = 0.05). The high prevalence of anemia, polyparasitism, and dietary insufficiency among children in rural coastal Kenya suggests that remedial interventions will need to address both diet and parasitic infections to effectively combat this significant health threat.
机译：众所周知，贫血会影响孩子的增长和发展，但并非所有的贫血都是由铁缺乏率引起的，并强调疾病疾病委员会和谁强调调查贫血症的其他贡献者。这一横断面的亚洲母婴队列在沿海肯尼亚的母婴队列评估了244名儿童，发现了185名（76％）以来的贫血至少在出生以来的一点。在2016年评估时，评价包括完整的血统计数，营养评估和对寄生感染的测试，重点是贫血的主要结果，定义为血红蛋白（HB）<11g / dl。评估的平均年龄为20.5 +/- 7个月。百分之九十五的血液范围内的寿命平均HB。调整年龄和性别，之前或目前的疟疾感染（之前：HBβ= -0.99,95％CI：-1.49至-0.49，P = 0.01），或者具有钩虫，richuris，酮，蛔虫，蛔虫的任何感染/或疟疾（β= -0.84,95％CI：-1.36至-0.33，P = 0.01）与电流降低有关。营养评价显示，每周含有下降的HB含量较少的儿童（P = 0.01）或鸡蛋（P = 0.01），喝更多的牛奶（P = 0.07），并吃更多的面包（P = 0.01） ，更有可能生活在经历粮食短缺的家庭中（P = 0.05）。农村沿海肯尼亚儿童贫血，息肉腺和膳食不足的高患病率表明，补救干预措施需要解决饮食和寄生虫感染，以有效地打击这一重大的健康威胁。

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