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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Tetanus Immunity Gaps in Children 5-14 Years and Men ≥ 15 Years of Age Revealed by Integrated Disease Serosurveillance in Kenya, Tanzania, and Mozambique
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Tetanus Immunity Gaps in Children 5-14 Years and Men ≥ 15 Years of Age Revealed by Integrated Disease Serosurveillance in Kenya, Tanzania, and Mozambique

机译:5-14岁儿童的破伤风免疫差距≥15岁,肯尼亚,坦桑尼亚和莫桑比克综合疾病血清血管爆发

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摘要

Recent tetanus cases associated with male circumcision in Eastern and Southern Africa (ESA) prompted an examination of tetanus immunity by age and sex using multiplex serologic data from community surveys in three ESA countries during 2012-2013. Tetanus seroprotection was lower among children 5-14 years versus 1-4 years of age in Kenya (66% versus 90%) and Tanzania (66% versus 89%), but not in Mozambique (91 % versus 88%), where children receive two booster doses in school. Among males > 15 years of age, tetanus seroprotection was lower than females in Kenya (45% versus 96%), Tanzania (28% versus 94%), and Mozambique (64% versus 90%). Tetanus immunity from infant vaccination doses wanes over time, and only women of reproductive age routinely receive booster doses. To prevent immunity gaps in older children, adolescents, and adult men, a life-course vaccination strategy is needed to provide the three recommended tetanus booster doses.
机译:最近在东部和南部非洲和南部的男性包皮环切(ESA)相关的破伤风病例促进了2012 - 2013年三个ESA国家的社区调查中的年龄和性别的破伤风疫苗。 在肯尼亚1-4岁的儿童和坦桑尼亚与坦桑尼亚66%的66%(66%对89%),但不在莫桑比克(66%),而不是在莫桑比克(与88%的88%),而不是88%) 在学校接受两剂量剂量。 在男性> 15岁之间,Tetanus Seropotection低于肯尼亚的女性(45%与96%),坦桑尼亚(28%与94%),莫桑比克(64%对90%)。 婴儿疫苗接种的破伤风免疫剂剂量随着时间的推移,只有生殖年龄的女性常规接受增强剂量。 为防止年龄较大的儿童,青少年和成人男性的免疫差距,需要寿命疫苗接种策略来提供三种推荐的破伤风增强剂量。

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