...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Examination of Antibody Responses as a Measure of Exposure to Malaria in the Indigenous Batwa and Their Non-Indigenous Neighbors in Southwestern Uganda
【24h】

Examination of Antibody Responses as a Measure of Exposure to Malaria in the Indigenous Batwa and Their Non-Indigenous Neighbors in Southwestern Uganda

机译：检查乌干达西南部土着蝙蝠市和非土着邻居暴露于疟疾的抗体反应

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Understanding variations in malaria transmission and exposure is critical to identify populations at risk and enable better targeting of interventions. The indigenous Batwa of southwestern Uganda have a disproportionate burden of malaria infection compared with their non-indigenous neighbors. To better understand the individual- and community-level determinants of malaria exposure, a seroepidemiological study was conducted in 10 local council cells in Kanungu District, Uganda, in April 2014. The Batwa had twice the odds of being seropositive to two Plasmo-dium falciparum-specific antigens, apical membrane antigen-1 and merozoite surface protein-1_(19), compared with the non-indigenous Bakiga (odds ratio = 2.08, 95% confidence interval = 1.51-2.88). This trend was found irrespective of altitude level and after controlling for cell location. Seroconversion rates in the Batwa were more than twice those observed in the Bakiga. For the Batwa, multiple factors may be associated with higher exposure to malaria and antibody levels relative to their non-indigenous neighbors.
机译：了解疟疾传播和暴露的变化对于识别风险的人群至关重要，使得能够更好地瞄准干预措施。与非土着邻国相比，西南乌干达西南部的土着蝙蝠湾对疟疾感染的负担不成比例。为了更好地了解疟疾暴露的个人和社区级别决定因素，在2014年4月在乌干达的Kanungu区的10个地方理事会细胞中进行了一次血清术研究。BATWA对两种Plasmo-Dium恶性疟原虫进行血清阳性的几率与非本土bakiga（差距= 2.08,95％置信区间= 1.51-2.88）相比，特异性抗原，顶端膜抗原-1和Merozoite表面蛋白-1_（19）。发现这种趋势无论高原水平如何以及控制细胞位置。 BATWA中的Seroconversion速率超过了Bakiga中观察到的两倍。对于BATWA，多种因子可能与相对于其非土着邻居的疟疾和抗体水平较高。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号