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首页> 外文期刊>The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry >Depression is Associated with Increased Risk for Metabolic Syndrome in Latinos with Type 2 Diabetes
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Depression is Associated with Increased Risk for Metabolic Syndrome in Latinos with Type 2 Diabetes

机译：抑郁症与患有2型糖尿病的拉丁美洲代谢综合征的风险增加有关

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Objective: Latino adults are 66% more likely to have diabetes relative to non-Latino white adults. Prior research identifies depression as a significant risk factor for metabolic syndrome (MetS), but research examining this among Latinos is lacking. This study sought to examine the links between depression and MetS and clinically significant elevations in cardiovascular disease risk markers of MetS in a sample of community-dwelling older Latinos with type 2 diabetes. Methods: Participants were 332 community-dwelling older (>= 60 years) Latinos with type 2 diabetes who completed the nine-item Patient Health Questionnaire and received a health checkup assessing body mass index (BMI), triglyceride and high-density lipoprotein (HDL) cholesterol levels, and blood pressure. Logistic regression analysis compared MetS rates of those meeting criteria for depression with those who did not. Secondary analyses examined the associations between depression and individual MetS components. All analyses controlled for demographic (e.g., income, age) and other potential MetS risk factors (e.g., smoking status, physical activity, alcohol level consumption). Results: Depression was significantly associated with an increased risk of MetS (OR: 5.79; 95% CI: 1.32-25.42) and clinically significant elevations in triglycerides (OR: 2.71; 95% CI: 1.15-6.42) and reduced (HDL) cholesterol (OR: 2.46; 95% CI: 1.11-5.45). A significant association was not observed between depression and either BMI or hypertension. Conclusion: Depression is significantly linked to MetS, and most notably dyslipidemia, in older Latinos with diabetes. Causation, however, cannot be inferred from these analyses given the cross-sectional nature of the study. Future research should prospectively examine the directionality of this effect.
机译：目的：拉丁裔成年人患有相对于非拉丁裔白人成人的糖尿病患者患有66％。先前的研究将抑郁症识别为代谢综合征（METS）的显着危险因素，但缺乏拉丁美洲群体中的研究。该研究试图检查抑郁症和Mets之间的联系以及患有2型糖尿病型患者的历史旧的拉美裔样本中的心血管疾病风险标志中的临床显着高程。方法：参与者是332个社区住宅（> = 60年）拉丁裔，其中2型糖尿病患者完成了九项患者健康调查问卷，并接受了健康检查评估体重指数（BMI），甘油三酯和高密度脂蛋白（HDL ）胆固醇水平和血压。 Logistic回归分析与那些没有那些没有的人的抑郁症符合标准的大都会率比较。二次分析检查了抑郁和个人METS组件之间的关联。所有分析对人口统计（例如，收入，年龄）和其他潜在的危险因素（例如，吸烟状况，身体活动，酒精水平消费）控制。结果：抑郁症显着与Mets的风险增加（或：5.79; 95％CI：1.32-25.42）和甘油三酯（或：2.71; 95％CI：1.15-6.42）和减少（HDL）胆固醇的临床显着升高（或：2.46; 95％CI：1.11-5.45）。抑郁症和BMI或高血压之间未观察到显着关联。结论：抑郁症与糖尿病患者较老的拉丁美洲人，最常见的血脂血症与Mets，最显着的血脂血症有显着挂钩。然而，由于研究的横截面性质，因此不能从这些分析中推断出来。未来的研究应潜在检查这种效果的方向性。

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