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首页> 外文期刊>The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry >Two Interventions for Patients With Major Depression and Severe Chronic Obstructive Pulmonary Disease: Impact on Quality of Life
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Two Interventions for Patients With Major Depression and Severe Chronic Obstructive Pulmonary Disease: Impact on Quality of Life

机译：治疗重大抑郁和严重慢性阻塞性肺病患者的两种干预：对生活质量的影响

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Objective: Clinically significant depression occurs in approximately 40% of chronic obstructive pulmonary disease (COPD) patients, and both illnesses severely impair quality of life. This study tests the hypothesis that problem-solving integrated with a treatment adherence intervention, the Problem Solving-Adherence (PSA), is superior to a personalized treatment adherence intervention, the Personalized Intervention for Depressed Patients with COPD (PID-C), alone in improving quality of life in depressed COPD patients. Methods: After screening 633 admissions for acute rehabilitation, we studied quality of life in 87 participants with major depression (by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) and severe COPD randomly assigned to 14 sessions of PID-C or PSA over 26 weeks. Quality of life was assessed using the Word Health Organization Quality of Life-BREF at baseline and weeks 10, 14, and 26. Results: The hypothesis was not supported. Exploratory latent class growth modeling identified two quality of life trajectories. In 80.5% of participants, quality of life remained unchanged and improved in the remaining 19.5% during the first 14 weeks. Patients with a stable quality trajectory had higher quality of life at baseline and a stronger sense of personal agency. Conclusion: Maintaining quality of life is a favorable outcome in depressed patients with COPD whose course is one of deterioration. These findings highlight the usefulness of PID-C, an easy to learn, personalized adherence enhancement intervention that, after further testing, may be integrated into the rehabilitation and care of depressed COPD patients.
机译：目的：临床显着的抑郁症发生在大约40％的慢性阻塞性肺病（COPD）患者中，疾病严重损害了生活质量。本研究测试了与治疗依从性干预集成的问题解决的假设，解决问题 - 遵守（PSA），优于个性化治疗依从性干预，单独抑制（PID-C）的抑郁症患者的个性化干预提高抑郁症COPD患者的生活质量。方法：筛选急性康复的633次入院后，我们研究了87名参与者的生活质量，主要抑郁症（通过精神障碍的诊断和统计手册，第四版）和严重的COPD随机分配到26个PID-C或PSA的14个会议周。利用基线的卫生组织的卫生组织质量评估生活质量和数周10,14和26日期。结果：不支持假设。探索性潜在增长模型确定了两个生活轨迹的质量。在80.5％的参与者中，在前14周内，剩余的19.5％的生活质量保持不变和改善。稳定质量轨迹的患者在基线和更强烈的个人机构感具有更高的生活质量。结论：维持生命质量是抑郁症患者的抑郁症患者，其课程是恶化之一。这些发现突出了PID-C的有用性，易于学习，个性化的依从性增强干预，在进一步测试之后，可以融入抑郁的COPD患者的康复和照顾。

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