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首页> 外文期刊>The Australian Journal of Pharmacy >Lipidil's key role in dyslipidaemia
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Lipidil's key role in dyslipidaemia

机译:Lipidil在血脂血症的关键作用

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摘要

THE most recent update of lipid management guidelines by the National Heart Foundation of Australia and the Cardiac Society of Australia and New Zealand further underlined the value of fibrates in reducing cardiovascular risk in those with type 2 diabetes, high triglyceride levels, low HDL (high-density lipoprotein) cholesterol, or in those who are overweight. These 2005 updates also amended previous advice, which recommended caution when combining fibrates with statins due to the risk of rhabdomyolysis, by noting lower risk of rhabdomyolysis when fenofibrate is used instead of gemfibrozil with a statin. This is an important issue for pharmacists who may witness a trend towards replacing gemfibrozil therapy with fenofibrate for this reason, as well as the fact that fenofibrate is taken as a once-daily tablet and gemfibrozil is taken twice-daily-an important consideration in terms of compliance.
机译:澳大利亚国家心脏基金会最近的脂质管理指南更新和澳大利亚心脏会和新西兰的心脏会产生了下划线在减少2型糖尿病,高甘油三酯水平,低HDL(高)中降低了匹配的心血管风险的价值 密度脂蛋白)胆固醇,或在超重的人中。 这些2005年的更新还修改了以前的建议,这推荐了在使用横纹肌溶解的风险时与他汀类药物相结合时,通过注意使用肾红皂酸酯的风险,而不是用他汀类药物的Gemfibrozil的横纹肌溶解的风险降低。 这对药剂师来说,这是可能证明趋势造成掺入食纤维的趋势的药剂师,以及非洲纤维酸盐作为曾经每日片剂和Gemfibrozil的事实进行了两次 - 每日两次 - 这是一个重要的考虑 合规性。

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