...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The anatomical record: advances in integrative anatomy and evolutionary biology >The Amniote Oculomotor Complex
【24h】

The Amniote Oculomotor Complex

机译：amniote动眼镜复合物

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ABSTRACT The oculomotor (OM) complex is a combination of somatic and parasympatethic neurons. The correct development and wiring of this cranial pair is essential to perform basic functions: eyeball and eyelid movements, pupillary constriction, and lens accommodation. The improper formation or function of this nucleus leads pathologies such as strabismus. We describe the OM organization and function in different vertebrate brains, including chick, mouse, and human. The morphological localization is detailed, as well as the spatial relation with the trochlear nucleus in order to adjust some misleading anatomical topographic descriptions. We detailed the signaling processes needed for the specification of the OM neurons. The transcriptional programs driven the specification and differentiation of these neurons are partially determined. We summarized recent genetic studies that have led to the identification of guidance mechanisms involved in the migration, axon pathfinding, and targeting of the OM neurons. Finally, we overviewed the pathology associated to genetic malformations in the OM development and related clinical alterations. Anat Rec, 302:446–451, 2019. ? 2018 Wiley Periodicals, Inc.
机译：摘要血管运动（OM）复合物是体细胞和副族苷神经元的组合。这个颅对的正确开发和接线对于执行基本功能至关重要：眼球和眼睑运动，瞳孔收缩和透镜。该核的不正确的形成或功能导致斜视等病理。我们描述了不同脊椎动物大脑的OM组织和功能，包括小鸡，鼠标和人。形态定位是详细的，以及与Trochlear核的空间关系，以调整一些误导性的解剖学图解描述。我们详细介绍了OM神经元规范所需的信号传导过程。转录程序驱动了这些神经元的说明书和分化部分确定。我们总结了最近的遗传研究，导致识别迁移，轴突探测和统计均神经元的引导机制。最后，我们概述了与OM发展中的遗传畸形相关的病理学和相关的临床改变。 ANAT REC，302：446-451,2019。 2018年Wiley期刊，Inc。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号