Cost-effectiveness of risk-reducing surgeries in preventing hereditary breast and ovarian cancer

Schrauder Michael G.; Brunel-Geuder Lisa; Haeberle Lothar; Wunderle Marius; Hoyer Juliane; Reis Andre; Schulz-Wendtland Ruediger; Beckmann Matthias W.; Lux Michael P.

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Cost-effectiveness of risk-reducing surgeries in preventing hereditary breast and ovarian cancer

机译：减少风险降低手术的成本效益，防止遗传性乳腺癌和卵巢癌

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Objectives: Risk-reducing surgeries are a feasible option for mitigating the risk in individuals with inherited susceptibility to cancer, but are the procedures cost-effective in the current health-care system in Germany? This study compared the health-care costs for bilateral risk-reducing mastectomy (BRRM) and risk-reducing (bilateral) salpingo-oophorectomy (RRSO) with cancer treatment costs that could potentially be prevented.

机译：目标：减轻风险的手术是可行的选择，可在遗传癌症遗传性易感性中减轻个人的风险，但是该程序是否在德国当前的医疗保健系统中具有成本效益？本研究比较了双侧风险降低乳房切除术（BRRM）和减少风险降温（双侧）Salpingo-Oophorectomy（RRSO）的医疗保健成本，其可能被妨碍癌症治疗费用。

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来源
《The Breast :》 |2017年第2017期|共6页
作者
Schrauder Michael G.; Brunel-Geuder Lisa; Haeberle Lothar; Wunderle Marius; Hoyer Juliane; Reis Andre; Schulz-Wendtland Ruediger; Beckmann Matthias W.; Lux Michael P.;
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作者单位

Friedrich Alexander Univ Erlangen Nurnberg FAU Dept Obstet &

Gynecol Erlangen Univ Hosp Univ;

Friedrich Alexander Univ Erlangen Nurnberg FAU Dept Obstet &

Gynecol Erlangen Univ Hosp Univ;

Friedrich Alexander Univ Erlangen Nurnberg FAU Dept Obstet &

Gynecol Erlangen Univ Hosp Univ;

Friedrich Alexander Univ Erlangen Nurnberg FAU Dept Obstet &

Gynecol Erlangen Univ Hosp Univ;

Friedrich Alexander Univ Erlangen Nurnberg FAU Inst Human Genet Univ Breast Ctr Franconia;

Friedrich Alexander Univ Erlangen Nurnberg FAU Inst Human Genet Univ Breast Ctr Franconia;

Friedrich Alexander Univ Erlangen Nurnberg FAU Inst Radiol Erlangen Univ Hosp Univ Breast Ctr;

Friedrich Alexander Univ Erlangen Nurnberg FAU Dept Obstet &

Gynecol Erlangen Univ Hosp Univ;

Friedrich Alexander Univ Erlangen Nurnberg FAU Dept Obstet &

Gynecol Erlangen Univ Hosp Univ;

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原文格式 PDF
正文语种 eng
中图分类胸部外科学;
关键词
Breast cancer; Ovarian cancer; Genetic counseling; Genetic testing; Cost-effectiveness; BRCA;

机译：乳腺癌;卵巢癌;遗传咨询;基因检测;成本效益;BRCA;

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专利

1. Cost-effectiveness of risk-reducing surgeries in preventing hereditary breast and ovarian cancer [J] . Schrauder Michael G., Brunel-Geuder Lisa, Haeberle Lothar, The Breast : . 2017,第期

机译：减少风险降低手术的成本效益，防止遗传性乳腺癌和卵巢癌
2. Perioperative Management of Women Undergoing Risk-reducing Surgery for Hereditary Breast and Ovarian Cancer [J] . AlHilli Mariam M., Al-Hilli Zahraa Journal of minimally invasive gynecology . 2019,第2期

机译：围手术期管理遗传乳腺癌和卵巢癌的降低疾病降低手术
3. Mullerian intra-abdominal carcinomatosis in hereditary breast ovarian cancer syndrome: implications for risk-reducing surgery [J] . Casey Murray Joseph, Colanta Agnes B. Familial cancer . 2016,第3期

机译：遗传性乳腺癌卵巢癌综合征中的苗勒氏腹腔内癌变：对降低风险的手术的意义
4. Visual Analytic Methods for Hereditary Breast and Ovarian Cancer Risk Assessment [C] . International Conference in Visualisation . 2009

机译：遗传性乳腺癌和卵巢癌风险评估的视觉分析方法
5. Hereditary Breast and Ovarian Cancer Risk Assessment at Community Imaging Centers [D] . ?Kellams, Carrie A. 2020

机译：遗传性乳腺癌和卵巢癌的风险评估在社区影像中心
6. Risk-reducing surgery in hereditary gynecological cancer: Clinical applications in Lynch syndrome and hereditary breast and ovarian cancer [O] . MASATAKA ADACHI, KOUJI BANNO, MEGUMI YANOKURA, -1

机译：遗传性妇科癌症的降低风险的手术：Lynch综合征以及遗传性乳腺癌和卵巢癌的临床应用
7. Concerns and Expectations of Risk-Reducing Surgery in Women with Hereditary Breast and Ovarian Cancer Syndrome [O] . Paola Modaffari, Riccardo Ponzone, Alberta Ferrari, 2019

机译：遗传性乳腺癌和卵巢癌综合征的妇女风险减少手术的担忧和期望
8. Modifiers of the Efficacy of Risk-Reducing Salpingo-Oophorectomy for the Prevention of Breast and Ovarian Cancer in Carriers of BRCA1 and BRCA2 Mutations [R] . Kauff, N. D. 2008

机译：降低风险的salpingo-Opherectomy用于预防BRCa1和BRCa2突变携带者的乳腺癌和卵巢癌的修饰物

Cost-effectiveness of risk-reducing surgeries in preventing hereditary breast and ovarian cancer

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