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首页> 外文期刊>The clinical respiratory journal. >Weaning attempts, cough strength and albumin are independent risk factors of reintubation in medical patients
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Weaning attempts, cough strength and albumin are independent risk factors of reintubation in medical patients

机译：断奶尝试，咳嗽强度和白蛋白是医学患者重新涂布的独立风险因素

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Abstract Background Reintubation is associated with increased hospital mortality. It is necessary to identify risk factors associated with reintubation. Methods A prospective observational study was performed in a respiratory intensive care unit. Medical patients who successfully completed a spontaneous breathing trial (SBT) were enrolled. Before extubation, age, gender, vital signs, acute physiology and chronic health evaluation II score, SBT attempts, cough peak flow, arterial blood gas tests and albumin were recorded. Results We enrolled 139 patients. Of these, 22 (15.8%) patients experienced reintubation within 72 hours after extubation. SBT attempts (odds ratio [OR]?=?1.446, 95% confidence interval [CI]: 1.095‐1.910), cough peak flow (OR?=?0.975, 95% CI: 0.956‐0.994) and albumin (OR?=?0.847, 95% CI: 0.752‐0.954) were independent risk factors for reintubation. In patients with 1, 2 and ≥3 SBT attempts, reintubation rates were 7.3%, 21.1% and 45.8%, respectively ( P ??.01). In patients with cough peak flow ≤60, 61‐89 and ≥90 L/min, reintubation rates were 29.4%, 16.7% and 1.9%, respectively ( P ??.01). In patients with albumin ≤25, 26‐30 and ≥31 g/L, reintubation rates were 32.4%, 11.1% and 9.8%, respectively ( P ?=?.01). Conclusions Multiple SBT attempts, weak cough and low albumin were associated with increased reintubation in medical patients. This study provides information for clinical practitioners in the consideration of patient extubation.
机译：抽象背景重新涂布与增加的医院死亡率增加有关。有必要识别与重新涂布相关的风险因素。方法在呼吸密集护理单位进行预期观察研究。已成功完成自发呼吸试验（SBT）的医疗患者。在拔管前，年龄，性别，生命体征，急性生理学和慢性健康评估II得分，记录SBT尝试，咳嗽峰流量，动脉血液试验和白蛋白。结果我们注册了139名患者。其中22例（15.8％）患者在拔管后72小时内经历了重新涂布。 SBT尝试（赔率比[或]？=？1.446,95％置信区间[CI]：1.095-1.910），咳嗽峰流量（或？=α= 0.975,95％CI：0.956-0.994）和白蛋白（或？= ？0.847,95％CI：0.752-0.954）是重新涂露的独立风险因素。在1,2和≥3sBT的患者中，重新孵化率分别为7.3％，21.1％和45.8％（P？＆ 01）。在咳嗽峰流量≤60,61-89和≥90升/分钟的患者中，重新孵化率分别为29.4％，16.7％和1.9％（P？＆ 01）。在白蛋白≤25,26-30和≥31g/ L的患者中，重新孵化率分别为32.4％，11.1％和9.8％（P？= 01）。结论多重SBT尝试，弱咳嗽和低白蛋白与医疗患者的重新涂布增加有关。本研究为临床从业者在考虑患者拔管时提供了临床从业者的信息。

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