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首页> 外文期刊>The British Journal of Nutrition >Physiological responses to maximal eating in men
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Physiological responses to maximal eating in men

机译:男性最大饮食的生理反应

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摘要

This study investigated metabolic, endocrine, appetite and mood responses to a maximal eating occasion in fourteen men (mean: age 28 (sd5) years, body mass 77 center dot 2 (sd6 center dot 6) kg and BMI 24 center dot 2 (sd2 center dot 2) kg/m(2)) who completed two trials in a randomised crossover design. On each occasion, participants ate a homogenous mixed-macronutrient meal (pizza). On one occasion, they ate until 'comfortably full' (ad libitum) and on the other, until they 'could not eat another bite' (maximal). Mean energy intake was double in the maximal (13 024 (95 % CI 10 964, 15 084) kJ; 3113 (95 % CI 2620, 3605) kcal) compared with thead libitumtrial (6627 (95 % CI 5708, 7547) kJ; 1584 (95 % CI 1364, 1804) kcal). Serum insulin incremental AUC (iAUC) increased approximately 1 center dot 5-fold in the maximal compared withad libitumtrial (mean:ad libitum43 center dot 8 (95 % CI 28 center dot 3, 59 center dot 3) nmol/l x 240 min and maximal 67 center dot 7 (95 % CI 47 center dot 0, 88 center dot 5) nmol/l x 240 min,P< 0 center dot 01), but glucose iAUC did not differ between trials (ad libitum94 center dot 3 (95 % CI 30 center dot 3, 158 center dot 2) mmol/l x 240 min and maximal 126 center dot 5 (95 % CI 76 center dot 9, 176 center dot 0) mmol/l x 240 min,P= 0 center dot 19). TAG iAUC was approximately 1 center dot 5-fold greater in the maximalv.ad libitumtrial (ad libitum98 center dot 6 (95 % CI 69 center dot 9, 127 center dot 2) mmol/l x 240 min and maximal 146 center dot 4 (95 % CI 88 center dot 6, 204 center dot 1) mmol/l x 240 min,P< 0 center dot 01). Total glucagon-like peptide-1, glucose-dependent insulinotropic peptide and peptide tyrosine-tyrosine iAUC were greater in the maximal compared withad libitumtrial (P< 0 center dot 05). Total ghrelin concentrations decreased to a similar extent, but AUC was slightly lower in the maximalv.ad libitumtrial (P= 0 center dot 02). There were marked differences on appetite and mood between trials, most notably maximal eating caused a prolonged increase in lethargy. Healthy men have the capacity to eat twice the energy content required to achieve comfortable fullness at a single meal. Postprandial glycaemia is well regulated following initial overeating, with elevated postprandial insulinaemia probably contributing.
机译:本研究调查了十四名男性的最大进食场合的代谢,内分泌,食欲和情绪反应(平均:28岁(SD5)年,体重77中心点2(SD6中心点6)KG和BMI 24中心点2(SD2中心点2)kg / m(2))在随机交叉设计中完成了两项试验。在每个场合,参与者都吃了同质混合 - Macronutient粉(披萨)。有一次,它们直到“舒适地满了”(可怕的人),另一个,直到他们“无法吃另一箱(最大)。最大值(13 024(95%CI 10 964,15 084)Kj; 3113(95%CI 2620,3605)KCAL)与雷维润(6627(95%CI 5708,7547)KJ;; 1584(95%CI 1364,1804)Kcal)。血清胰岛素增量AUC(IAUC)在最大化的比较中增加了大约1个中心点5倍,与Libitumtrial相比(平均值:AD Libitum43中心点8(95%CI 28中心点3,59中心点3)Nmol / Lx 240 min和最大67中心点7(95%CI 47中心点0,88中心点5)Nmol / Lx 240 min,P <0中心点01),但葡萄糖IAC在试验之间没有区别(AD Libitum94中心点3(95%CI) 30中心点3,158中心点2)MMOL / LX 240分钟和最大126中心点5(95%CI 76中心点9,176中心点0)MMOL / LX 240 min,P = 0中心点19)。 Maximalv.ad IAUC在Maximalv.AD中大约1个中心点5倍。 %CI 88中心点6,204中心点1)MMOL / LX 240 min,P <0中心点01)。与Libitumtrial的最大相比,总胰高血糖素肽-1,葡萄糖依赖性胰岛素肽和肽酪氨酸酪氨酸Iac在最大相比(P <0中心点05)。总核细胞素浓度降低到相似的程度,但是Maximalv.AC中的AUC略低于libitumtrial(p = 0中心点02)。试验之间的食欲和情绪有明显的差异,最大的最大进食导致嗜睡的长时间增加。健康的人有能力吃两倍的能量内容,以便在一顿饭时实现舒适的丰满度。在初始暴饮暴食之后,餐后糖类症是良好的调节,后胰岛素内血症升高可能是有贡献的。

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