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首页> 外文期刊>The Canadian journal of hospital pharmacy. >Antibiotic Use and Need for Antimicrobial Stewardship in Long-Term Care
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Antibiotic Use and Need for Antimicrobial Stewardship in Long-Term Care

机译：抗生素使用和需要长期护理的抗微生物管道

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Background: Antimicrobial stewardship may be important in long-term care facilities because of unnecessary or inappropriate antibiotic use observed in these residents, coupled with their increased vulnerability to health care—associated infections. Objectives: To assess antibiotic use in a long-term care facility in order to identify potential antimicrobial stewardship needs. Methods: A retrospective descriptive study was conducted at the Veterans Centre, a long-term care facility at Sunnybrook Health Sciences Centre, Toronto, Ontario. All residents taking one or more antibiotics (n = 326) were included as participants. Antibiotic-use data for patients residing in the facility between April 1, 2011, and March 31, 2012, were collected and analyzed. Results: Totals of 358 patient encounters, 835 antibiotic prescriptions, and 193 positive culture results were documented during the study period. For 36% (302/835) of antibiotic prescriptions, the duration was more than 7 days. Cephalosporins (30%; 251/835) and fluoroquinolones (28%; 235/835) were the most frequently prescribed antibiotic classes. Urine was the most common source of samples for culture (60%; 116/193). Conclusions: Characteristics of antimicrobial use at this long-term care facility that might benefit from further evaluation included potentially excessive use of fluoroquinolones and cephalosporins and potentially excessive duration of antibiotic use for individual patients.
机译：背景：在这些居民中观察到的长期护理设施中，抗菌管道可能是重要的，因为这些居民观察到不必要或不恰当的用途，同时加上其对卫生保健相关感染的增加的脆弱性。目标：评估长期护理设施的抗生素使用，以识别潜在的抗微生物管制需求。方法：在安大略省多伦多多伦多的长期护理设施，在Veterans Center下进行了回顾性描述性研究。作为参与者将所有服用一种或多种抗生素（n = 326）的居民。收集和分析了居住在2011年4月1日至2012年3月31日之间的患者的抗生素使用数据。结果：在研究期间记录了358例患者遭遇，835例抗生素处方和193个阳性培养结果的总数。对于36％（302/835）的抗生素处方，持续时间超过7天。头孢菌素（30％; 251/835）和氟代喹啉（28％; 235/835）是最常见的抗生素类。尿液是培养物质中最常见的来源（60％; 116/193）。结论：这种长期护理设施的抗菌药物的特征可能受益于进一步评估，包括含有氟喹诺酮和头孢菌素和头孢菌素的潜在过量使用，以及对个体患者的抗生素用途过度持续时间。

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