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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >P.083 Radiology reporting of low-grade glioma growth underestimates tumor expansion
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P.083 Radiology reporting of low-grade glioma growth underestimates tumor expansion

机译：P.083低级胶质瘤生长的放射学报告低估肿瘤扩张

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Background: Surveillance by serial magnetic resonance imaging (MRI) is important in the management of diffuse low-grade gliomas (LGGs). Radiological interpretations of LGG scans, however, are typically qualitative and difficult to use clinically. Methods: We retrospectively compared radiological interpretations of LGG growth/stability to volume change measured by manual segmentation. Tumour diameter was measured to evaluate methods for assessing glioma progression, including RECIST criteria, Macdonald/RANO criteria, and mean tumour diameter/ellipsoid method. Results: Tumours evaluated as stable by radiologists grew a median 5.1 mL (11.1%) relative to the comparison scan. Those evaluated as having grown increased by 13.3 mL (23.7%). Diameter-based measurements corresponded well but tended to overestimate segmented volumes, and overestimation error increased with tumour size. Agreement with segmented volume improved from a mean difference of 17.6 to 4.5 to 3.9 mm for diameter and from 104.0 to 25.3 to 15.9 mL for volume with measurements in one, two, and three dimensions. Conclusions: Given evidence that LGG volume and growth are prognostic factors, lesions should be accurately measured. Current radiological reporting workflows fail to appreciate and communicate the true expansion of LGGs. Volumetric analysis remains the gold standard for growth assessment, but diametric measurements in three dimensions may be an acceptable alternative.
机译：背景：通过串行磁共振成像（MRI）的监测在弥漫性低级GLIMAS（LGGS）的管理中是重要的。然而，LGG扫描的放射性解释通常是定性且难以在临床上使用。方法：我们回顾性地比较了通过手动分割测量的LGG增长/稳定性的放射性解释。测量肿瘤直径以评估评估胶质瘤进展的方法，包括再次标准，麦克唐纳/ RANO标准和平均肿瘤直径/椭圆形方法。结果：肿瘤作为放射科医生稳定评价的肿瘤相对于比较扫描增长了5.1ml（11.1％）。评价为生长的那些增加13.3ml（23.7％）。基于直径的测量良好，但倾向于估计分段体积，并且肿瘤大小增加了高估误差。对于直径的平均差异的分段差异的协议改善了直径为17.6至4.5至3.9毫米，体积的104.0至25.3至15.9 ml，其中一个，两个和三维测量值。结论：鉴于LGG体积和生长是预后因素的证据，应准确测量病变。目前的放射性报告工作流程未能升值和传达LGGS的真正扩展。体积分析仍然是生长评估的金标准，但三个维度的直径测量可能是可接受的替代方案。

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