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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Clinical Utility of the Envelope Task in Mild Cognitive Impairment and Dementia
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Clinical Utility of the Envelope Task in Mild Cognitive Impairment and Dementia

机译：轻度认知障碍和痴呆症包络任务的临床效用

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摘要

Objective: Prospective memory (PM) is a cognitive function defined as the ability to perform an intention at an appropriate moment in the future. In the aging population, PM is essential for maintaining independent daily living. Introduced as a simple and quick way to assess PM in clinical settings, the envelope task has to date received very limited empirical and practical interest. Methods: The present study investigated the task's clinical utility in detecting PM impairment in a sample composed of 49 healthy older adults (OA), 41 patients with Alzheimer's disease, and 64 individuals with amnestic and nonamnestic mild cognitive impairment (MCI) of heterogeneous etiology: 17 of idiopathic nature, 20 presenting an idiopathic rapid-eye movement sleep behaviour disorder, and 27 patients diagnosed with idiopathic Parkinson's disease. Results: The envelope task was highly sensitive and specific in discriminating Alzheimer's disease patients from OA. Although it was specific in distinguishing MCI individuals from OA, its sensitivity was modest, especially in patients presenting a nonamnestic MCI subtype. Conclusions: Given its high specificity and simple low-cost administration procedure, the envelope task is a promising instrument for clinicians who seek to rapidly assess PM impairment in their daily practice.
机译：目的：潜在记忆（PM）是一种认知函数，被定义为在未来适当的时刻在未来执行意图的能力。在老龄化人口中，PM对于维持独立日常生活至关重要。作为评估PM在临床环境中的简单且快速的方式，信封任务必须接受非常有限的经验和实际兴趣。方法：本研究调查了任务的临床实用性在由49名健康老年人（OA），41例阿尔茨海默病患者组成的样品中检测PM损伤，以及64名具有异质病因的Amnestic和NonnestMics认知障碍（MCI）的人： 17种特发性性质，20例呈现特发性快速眼动睡眠行为障碍，27名患者被诊断出患有特发性帕金森病。结果：信封任务对来自OA的阿尔茨海默病患者的患者具有高度敏感和特异性。虽然它是特定的，但在从OA区分MCI个体时，它的敏感性是适度的，特别是在呈现NonamestM MCI亚型的患者中。结论：鉴于其高特异性和简单的低成本管理程序，信封任务是临床医生的有希望的仪器，该临床医生在日常练习中寻求迅速评估PM损伤。

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