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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Outcome Comparison of Nerve Transfer with Different Donor Nerves in a Rat Model
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Outcome Comparison of Nerve Transfer with Different Donor Nerves in a Rat Model

机译：大鼠模型中不同供体神经的神经转移的结果比较

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Objective: The phrenic nerve and the contralateral seventh cervical (C7) nerve root are the most commonly used donor nerves in the treatment of total brachial plexus avulsion. The aim of this study was to determine if the phrenic nerve or the contralateral C7 nerve root yields a superior outcome for nerve transfer. Methods: A total of 60 Sprague-Dawley rats were randomly assigned to 1 of 3 groups. In Group A the phrenic nerve was used as the donor nerve; in Group B the contralateral C7 nerve root nerve was used as the donor nerve; in Group C the nerve was directly sutured. The results of behavioral assessment, electrophysiology, histology, nerve fiber count and muscle weight at 24 weeks postoperatively were recorded. Results: Group A showed a faster recovery time compared to Group B; however Group B showed a better functional recovery at the final outcome assessment compared to Group A. Conclusion: The contralateral C7 nerve root was better as the donor nerve for nerve transfer in the treatment of total brachial plexus avulsion.
机译：目的：膈神经和对侧第七宫颈（C7）神经根部是最常用的供体神经治疗总臂丛丛撕裂。本研究的目的是确定膈神经或对侧C7神经根部是否产生神经转移的优异结果。方法：总共60只Sprague-Dawley大鼠随机分配给3组中的1只。在组中，使用膈神经作为供体神经;在B组中，将对侧C7神经根神经用作供体神经;在C组中，神经直接缝合。记录了行为评估，电生理学，组织学，神经纤维计数和肌肉重的结果。记录了术后24周。结果：A组与B组相比显示了更快的恢复时间;然而，与A组相比，B组在最终结果评估中表现出更好的功能恢复。结论：对侧C7神经根部作为神经转移的供体神经，在治疗总臂丛神经疏血中。

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