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首页> 外文期刊>The journal of alternative and complementary medicine: research on paradigm, practice, and policy >The Effect of T'ai Chi Exercise on Lipid Profiles: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
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The Effect of T'ai Chi Exercise on Lipid Profiles: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

机译:T'ai Chi运动对脂质谱的影响:随机临床试验的系统回顾与荟萃分析

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Background: Cardiovascular disease is a common health problem resulting from many factors, including dyslipidemia. T'ai chi is one of the interventions assigned to improve lipid profiles and other physical outcomes. However, conflicting results might be attributed to different study designs and interventional approaches. A systematic review and meta-analysis are needed to evaluate existing evidence. Objective: The aim of this systematic review and meta-analysis is to evaluate existing randomized clinical trials (RCTs) regarding the overall effect of t'ai chi exercise on lipid profiles. Methods: Electronic databases (MEDLINE and Cumulative Index to Nursing and Allied Health Literature) were searched. The authors included only English peer reviewed published RCTs that used a t'ai chi intervention and high-density lipoprotein cholesterol (HDL-C) as the primary outcome along with low-density lipoprotein cholesterol (LDL-C) and/or total cholesterol (TC) as secondary outcomes. Results: The authors identified 37 potentially eligible studies. Only eight RCTs were eligible for their qualitative review, and seven studies were eligible for meta-analysis. The included studies were rated as having a low risk of bias. Despite the overall low risk of bias, all studies failed to blind participants to group assignment and were generally unclear about whether they were selectively reporting data. A fixed effect model ( I ~(2) = 38.16%) demonstrated a small positive effect of t'ai chi on HDL-C (Cohen d = 0.12; standard error [SE] = 0.067; p = 0.037). A random effect model demonstrated a medium effect and small effect for LDL-C (Cohen d = 0.47; SE = 0.347; p = 0.089) and TC (Cohen d = 0.34; SE = 0.225; p = 0.066), respectively. Conclusion: T'ai chi may potentially be beneficial on lipid profiles across different age groups and populations. Although there were conflicting results regarding the effect of t'ai chi on lipid profiles, the majority of studies had at least a small positive effect indicating a potential positive effect of t'ai chi on HDL-C, LDL-C, and/or TC. Therefore, further research is needed to confirm the small positive effect of t'ai chi on lipid profiles found in this review.
机译:背景:心血管疾病是许多因素导致的常见健康问题,包括血脂血症。 T'Ai Chi是分配给改善脂质谱和其他物理结果的干预措施之一。然而,相互冲突的结果可能归因于不同的研究设计和介入方法。需要系统审查和荟萃分析来评估现有证据。目的:这种系统审查和荟萃分析的目的是评估关于T'Ai Chi运动对脂质谱的总体效果的现有随机临床试验(RCT)。方法:搜查了电子数据库(MEDLINE和累计指数到护理和盟国健康文献)。作者仅包括英语同行评审的公开的RCT,其使用T'ai Chi干预和高密度脂蛋白胆固醇(HDL-C)作为主要结果以及低密度脂蛋白胆固醇(LDL-C)和/或总胆固醇( TC)作为二次结果。结果:作者确定了37项符合条件的研究。只有8个RCT有资格获得定性审查,七项研究有资格获得Meta分析。所附的研究被评为偏倚风险低。尽管偏差的总体风险较低,但所有研究都未能盲目参与分配,并且通常不清楚他们是否选择性地报告数据。固定效果模型(I〜(2)= 38.16%)表现出T'Ai Chi对HDL-C的浓度效果(Cohen D = 0.12;标准误差[SE] = 0.067; P = 0.037)。随机效果模型分别证明了LDL-C的中等效应和小效果(COHEN D = 0.47; SE = 0.347; P = 0.089)和TC(COHEN D = 0.34; SE = 0.225; P = 0.066)。结论:T'Ai Chi可能对不同年龄群和人群的脂质谱有益。虽然有关T'ai Chi对脂质谱的影响存在矛盾的结果,但大多数研究表明T'ai Chi对HDL-C,LDL-C和/或/或潜在的积极效果。 Tc。因此,需要进一步研究以确认T'Ai Chi对本综述中发现的脂质谱的小积极作用。

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