首页> 外文期刊>The Journal of Antibiotics: An International Journal >Two novel cyclic depsipeptides Xenematides F and G from the entomopathogenic bacterium Xenorhabdus budapestensis
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Two novel cyclic depsipeptides Xenematides F and G from the entomopathogenic bacterium Xenorhabdus budapestensis

机译:两种新型循环缺口辛酸酯F和G来自昆虫致病菌的Xenorhabdus budapestensis

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摘要

Two novel depsipeptides xenematides F and G (1, 2), were isolated from entomopathogenic Xenorhabdus budapestensis SN84 along with a known compound xenematide B. The structures of the two new molecules were elucidated using NMR, MS and Marfey's method. The xenematide G (2) contains alpha-aminoheptanoic acid, a non-protein amino acid that is rarely found in secondary metabolites from entomopathogenic bacteria. Xenematides F and G were tested for antibacterial activity. Xenematide G (2) exhibited moderate antibacterial activity.
机译:两种新的Depsipeptips辛次磷酸酯F和G(1,2)与昆虫疗法Xenorhabdus Budapestensis SN84一起分离,并与已知的化合物己酸酯B.使用NMR,MS和MARFEY的方法阐明了两种新分子的结构。 氧化羟哌啶G(2)含有α-氨基酸,一种很少在来自昆虫致病细菌的次生代谢物中发现的非蛋白质氨基酸。 测试Xenematides F和G用于抗菌活性。 西哌啶G(2)表现出中度抗菌活性。

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    Shenyang Agr Univ Dept Plant Protect Shenyang 110866 Liaoning Peoples R China;

    Shenyang Agr Univ Dept Plant Protect Shenyang 110866 Liaoning Peoples R China;

    Shenyang Agr Univ Dept Plant Protect Shenyang 110866 Liaoning Peoples R China;

    Shenyang Agr Univ Dept Plant Protect Shenyang 110866 Liaoning Peoples R China;

    Shenyang Agr Univ Dept Plant Protect Shenyang 110866 Liaoning Peoples R China;

    Shenyang Agr Univ Dept Plant Protect Shenyang 110866 Liaoning Peoples R China;

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  • 中图分类 药学;
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