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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Incidence of hypoglycemia in newborn infants identified as at risk
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Incidence of hypoglycemia in newborn infants identified as at risk

机译：新生儿婴儿的低血糖发病率被确定为风险

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Background:Temporary low plasma glucose concentrations are common in healthy newborns. Although there is no uniform definition of neonatal hypoglycemia, there is a consensus in the current literature that plasma glucose concentrations should be measured in infants at risk. Known risk groups for transient neonatal hypoglycemia include infants of diabetic mothers (IDM), large (LGA) or small (SGA) for gestational age and late preterm (LPT) infants. Objectives:The aim of this retrospective trial was to determine the incidence of hypoglycemia and the impact of the application of a 2011 revised guideline in respect of additional feeding or i.v. glucose administration, admission to a neonatal ward and the number of blood samples taken. Methods:During the period 1 January 2015 to 31 January 2016, the plasma glucose concentrations of all infants at risk were determined. They were screened over a period of 24 hours or until plasma glucose concentration was >45 mg/dL on three occasions. Hypoglycemia was defined as a plasma glucose concentration <40 mg/dL, regardless of the age of the infant. Results:One hundred and thirty-six (13.6%) out of 1017 newborns were identified as at-risk patients, 119 (87.5%) of whom were included in the final data evaluation. Ten study participants had more than one risk factor and 32 (26.9%) newborns (male:female = 1.1:1) had a total of 40 hypoglycemic episodes. Three (9.4%) out of these 32 newborns had to be transferred to the neonatal ward for i.v. glucose treatment. The mean number of blood samples taken was 7.6 +/- 2.4. Conclusions:The incidence of hypoglycemia in the studied infants at risk was 27%, and 19.7 blood samples had to be taken to detect one episode of low glucose concentration. Neonatal hypoglycemia can be recognized and avoided in time, which justifies the establishment of a standardized plasma glucose measurement protocol in newborn infants at risk. Brief Rationale Following a considerable number of sources, it is recommended that infants at risk be identified, low plasma glucose concentrations prevented and, if necessary, the affected neonates cared for. Our data show that the risk group for neonatal hypoglycemia comprised about one-tenth of all infants at our nursery and hypoglycemia occurred in one-fourth. These results are in accordance with the recommendations to implement this protocol as a screening tool in neonates.
机译：背景：临时低位血浆葡萄糖浓度在健康的新生儿中是常见的。虽然新生儿低血糖的定义没有均匀的定义，但目前文献中存在共识，血浆葡萄糖浓度应在风险上的婴儿中测量。瞬态新生儿低血糖症的已知风险群包括糖尿病母亲（IDM），大（LGA）或小（SGA）的婴儿，用于妊娠期和晚期早产（LPT）婴儿。目标：这种回顾性试验的目的是确定低血糖发生的发病率以及2011年修订指南的应用的影响以及额外喂养或i.v.葡萄糖给药，进入新生儿病房和血液样本的数量。方法：2015年1月1日至2016年1月31日，确定所有风险婴儿的血浆葡萄糖浓度。它们在24小时内筛选或直到三次血浆葡萄糖浓度> 45mg / dl。低血糖定义为血浆葡萄糖浓度<40mg / dl，无论婴儿的年龄如何。结果：1017名新生儿中的一百三十六（13.6％）被鉴定为风险患者，其中119名（87.5％）被列入最终数据评估。十个研究参与者有一个以上的风险因素和32名（26.9％）新生儿（男性：女性= 1.1：1）共有40个低血糖发作。这32个新生儿中的三（9.4％）必须转移到I.V的新生儿病房。葡萄糖治疗。所采用的平均血液样品数为7.6 +/- 2.4。结论：危险的研究中的低血糖发生的发病率为27％，并且必须采取19.7个血样来检测一种低葡萄糖浓度的一集。新生儿的低血糖可以及时认可和避免，这证明了在危险的新生儿标准化的血浆葡萄糖测量方案中建立了标准化的血浆葡萄糖测量方案。在相当数量的来源之后简要说明，建议鉴定风险的婴儿，防止血浆葡萄糖浓度低，并且如有必要，受影响的新生儿为受到关心的。我们的数据显示，新生儿低血糖症的风险组包含在我们的苗圃和低血糖中的所有婴儿约有十分之一。这些结果符合建议将本协议作为新生儿中的筛选工具实施。

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