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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Foetoscopic endotracheal occlusion (FETO) for severe isolated left-sided congenital diaphragmatic hernia: single center Polish experience
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Foetoscopic endotracheal occlusion (FETO) for severe isolated left-sided congenital diaphragmatic hernia: single center Polish experience

机译:Foetoscopic气管插管闭塞(FETO)用于严重的左侧左侧先天性膈膜疝:单中心波兰经验

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Objective: To present early experience with foetoscopic endotracheal occlusion (FETO) for congenital diaphragmatic hernia (CDH) in a new center in Poland. Methods: This was a prospective study in singleton pregnancies with CDH treated by FETO between 2014 and 2016 in the Medical University of Warsaw, Poland. FETO was carried out at 25.6-30.1 (median 27.7) weeks' gestation in 28 consecutive cases of isolated left-sided CDH with observed over expected lung area to head circumference ratio (o/e LHR) of 20.7-22.6 (median 18.9). Results: Neonatal survival rate was 46.4% (13/28) at the time of discharge. The median o/e LHR the day before balloon removal was 33.4 (19.7-57.5) and median gestational age at delivery was 34.7 (29.0-38.1) weeks. Comparison of the survivors and perinatal deaths showed no significant differences in median gestational age at FETO or median o/e LHR before FETO, but higher median gestational age at delivery (35.9, range 32.7-38.1 weeks vs. 33.2, range 29.0-37.7 weeks; p = .007) and o/e LHR before balloon removal (33.7, range 28.3-57.5 vs. 30.9, range 19.7-37.5;
机译:目的:在波兰新中心展示先天性膈疝(CDH)的早期经验。方法:这是2014年至2016年在波兰医科大学的2014年和2016年在2014年和2016年间依托的CDH治疗了辛格尔顿怀孕的前瞻性研究。依托在25.6-30.1周(中位数27.7)周龄,在28例分离左侧CDH的妊娠上进行妊娠,观察到预期的肺部面积为20.7-22.6(中位数18.9)。结果:排放时新生儿存活率为46.4%(13/28)。在气球去除前的第二天中位数O / E LHR为33.4(19.7-57.5),交货时的中位孕龄(29.0-38.1)周。幸存者和围产期死亡的比较表明,在胎儿之前的胎儿或中位数O / E LHR中位于胎儿或中位数的妊娠年龄没有显着差异,但在递送时的胎龄更高(35.9,范围32.7-38.1周与33.2,范围为29.0-37.7周; P = .007)和滚球去除前的O / E LHR(33.7,范围为28.3-57.5与30.9,范围19.7-37.5;

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