...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Treatment Sequencing in Advanced BRAF -Mutant Melanoma Patients: Current Practice in the United States
【24h】

Treatment Sequencing in Advanced BRAF -Mutant Melanoma Patients: Current Practice in the United States

机译：高级BRAF-矫正黑素瘤患者治疗测序：美国目前的实践

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Treatment of advanced BRAF -mutant melanoma has changed dramatically in the past 3 years thanks to the approval of new immunotherapy and targeted therapy agents. Objectives: The goal of our survey was to investigate when immunotherapy and targeted therapy are used in the management of advanced melanoma patients and whether differences exist between the types of setting. Methods: Oncologists from academic centers, community-based centers, and private clinics were invited to participate in an online survey. Survey questions addressed the proportion of BRAF-mutant patients per treatment line, proportion of patients on targeted therapy and immunotherapy available in the United States, and reasons for prescribing each drug class. Results: A total of 101 physicians completed the survey, of which 47 worked in a private clinic, 33 in an academic center, and 21 in a community-based center. Academic center participants tended to see more severe patients ( P P Conclusions: The findings illustrate the differences in treatment approach per type of setting, with patients in academic centers more likely to receive recently approved products or to be enrolled in clinical trials than those in community-based settings.
机译：背景：由于新型免疫疗法和有针对性的治疗剂的批准，过去3年进行了先进的BRAF-矫炼体黑素瘤的治疗。目的：我们的调查的目标是调查免疫疗法和靶向治疗用于治疗晚期黑素瘤患者的管理以及是否存在环境类型之间存在差异。方法：邀请基于学术中心，社区中心和私人诊所的肿瘤学家参加在线调查。调查问题涉及每次治疗线的BRAF-突变患者的比例，患者的靶向治疗和免疫疗法的比例，以及各种药物课程的原因。结果：共有101名医生完成调查，其中47名在私人诊所，33位在一个学术中心，21个在社区中心。学术中心参与者倾向于看到更严重的患者（PP得出结论：调查结果说明了每种类型的治疗方法的差异，学术中心的患者更有可能获得最近批准的产品或临床试验比社区中的临床试验 - 基于的设置。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号