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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Medications and Micronutrients: Identifying Clinically Relevant Interactions and Addressing Nutritional Needs
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Medications and Micronutrients: Identifying Clinically Relevant Interactions and Addressing Nutritional Needs

机译：药物和微量营养素：识别临床相关的相互作用并解决营养需求

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Objective: Prescription drug use is on the rise, and the use of dietary supplementation remains common. In the United States, more than half of all adults take a dietary supplement in any given month. As a result, drug-nutrient interactions are becoming an important consideration when pharmacists counsel patients about their drug regimens. We reviewed the literature to identify common and/or clinically relevant drug-nutrient interactions that pharmacists may encounter in practice. Data Sources: A MEDLINE search for English-language publications from 1970 through March 2017 was performed using search terms (and variations) related to drugs, medications, micronutrients, and interactions. Study Selection and Data Extraction: Relevant studies, case reports, and reviews describing drug-nutrient interactions were selected for inclusion. Data Synthesis: Some drug-nutrient interactions may result in micronutrient insufficiencies or even frank deficiencies, thereby necessitating augmentation with multivitamin/minerals or individual vitamin/mineral dietary supplements. This most often occurs with long-term therapy for chronic conditions, such as treatment with proton-pump inhibitors and histamine-2 receptor antagonists. In addition, some chronic diseases themselves, such as diabetes, may predispose patients to micronutrient insufficiencies, and dietary supplementation may be advisable. Conclusions: Drug-nutrient interactions can often be resolved through specific dosing strategies to ensure that the full effect of the medication or the dietary supplement is not compromised by the other. In rare cases, the dietary supplement may need to be discontinued or monitored during treatment. Pharmacists are in a key position to identify and discuss these drug-nutrient interactions with patients and the health care team.
机译：目的：处方药中的崛起，膳食补充剂的使用仍然很常见。在美国，超过一半的成年人在任何一个月内都会在任何一个月内服用膳食补充剂。因此，当药剂师患者关于其药物方案时，药物营养相互作用正在成为一个重要的考虑因素。我们审查了文献，以确定药剂师在实践中可能遇到的常见和/或临床相关的药物营养相互作用。数据来源：使用与药物，药物，微量营养素，微量营养素和相互作用相关的搜索条款（和变化）进行1970年3月的英语出版物的Medline搜索英语出版物。学习选择和数据提取：选择描述药物 - 营养相互作用的相关研究，病例报告和评论进行包合物。数据合成：一些药物营养相互作用可能导致微量营养素不足或甚至坦率的缺陷，从而需要使用多种维生素/矿物或矿物/矿物膳食补充剂进行增强。这通常发生在长期治疗慢性条件下，例如用质子泵抑制剂和组胺-2受体拮抗剂治疗。此外，一些慢性疾病本身，如糖尿病，可以使患者倾向于微量营养素不足，并且可以建议膳食补充剂。结论：药物 - 营养相互作用通常通过特定的给药策略来解决，以确保药物或膳食补充剂的全部效果不受其它损害。在极少数情况下，可能需要在治疗过程中停止或监测膳食补充剂。药剂师处于一个关键位置，以识别和讨论与患者和医疗保健团队的这些药物营养素相互作用。

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