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首页> 外文期刊>The Journal of Prosthetic Dentistry >Inhibition of denture plaque deposition on complete dentures by 2-methacryloyloxyethyl phosphorylcholine polymer coating: A clinical study
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Inhibition of denture plaque deposition on complete dentures by 2-methacryloyloxyethyl phosphorylcholine polymer coating: A clinical study

机译：用2-甲基丙烯酰氧基乙基磷胆碱涂料抑制义齿牙菌斑沉积在完全假牙上的抑制作用：临床研究

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Abstract Statement of problem Denture plaque-associated infections are regarded as a source of serious dental and medical complications in the elderly population. Methods of managing this problem are needed. Purpose The purpose of this clinical study was to evaluate the effects of treatment with a 2-methacryloyloxyethyl phosphorylcholine polymer, PMBPAz, on plaque deposition in complete dentures. Material and methods The study protocol was approved by the Ethics Committee of Showa University (#2013-013). Eleven individuals with maxillary complete dentures participated in this study. Their dentures were treated with PMBPAz, and the amount of denture plaque accumulation was evaluated by staining the denture surfaces with methylene blue after 2 weeks of denture usage. The same procedures were repeated to evaluate the original denture surfaces as a control. The image of the stained denture surface was captured using a digital camera, and the percentage of stained area, quantified as a pixel-based density, of the whole denture area (percentage of plaque index) was calculated for the mucosal and polished surfaces. To quantify the biofilm on the dentures, denture plaque biofilm was detached by ultrasonic vibration, resuspended in diluent, and measured with a microplate reader at an optical density of 620 nm. The effects of PMBPAz treatment on these variables were statistically analyzed with ANOVA (α=.05). Results The mean ±SD percentage of plaque index was 40.7% ±19.9% on the mucosal surfaces and 28.0% ±16.8% on the polished surfaces of the control denture. The mean percentage of plaque index of PMBPAz-treated dentures significantly decreased to 17.4%% ±12.0% on the mucosal surfaces ( P P Conclusions These results demonstrated the effectiveness of the treatment with the PMBPAz to inhibit the bacterial plaque deposition on complete dentures.
机译：摘要问题牙本质牙斑的牙齿相关的感染被认为是老年人人口严重牙科和医学并发症的来源。需要管理此问题的方法。目的该临床研究的目的是评估用2-甲基丙烯酰氧基乙基磷藻酸胆碱聚合物，PMBPAZ的处理对完整假牙的斑块沉积。材料和方法研究议定书由昭和大学的伦理委员会批准（＃2013-013）。具有上颌完整假牙的11个个人参与了这项研究。他们的假牙用PMBPAZ治疗，并通过在义齿使用2周后用亚甲基蓝染色义齿表面来评价义齿斑块积累的量。重复相同的程序以评估原始义齿表面作为对照。使用数码相机捕获染色的义肢表面的图像，并计算为粘膜和抛光表面的整个义齿区域（斑块指数百分比）的染色区域的百分比。为了量化假牙上的生物膜，通过超声波振动分离义齿斑块生物膜，重悬于稀释剂中，并以620nm的光密度用微孔板读取器测量。用ANOVA（α= 0.05）统计分析PMBPAZ处理对这些变量的影响。结果粘膜表面的平均值±SD百分比为粘膜表面的40.7％±19.9％，对照义齿的抛光表面上的28.0％±16.8％。 PMBPAZ处理假牙的斑块指数的平均百分比显着降低至粘膜表面上的17.4 %%±12.0％（P p结论这些结果证明了用PMBPAZ处理的有效性，以抑制完全假牙上的细菌斑块沉积。

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    Kenji Ikeya; Fuminori Iwasa; Yuuki Inoue; Miya Fukunishi; Nana Takahashi; Kazuhiko Ishihara; Kazuyoshi Baba;

  • 作者单位

    Department of Prosthodontics School of Dentistry Showa University;

    Department of Prosthodontics School of Dentistry Showa University;

    Department of Materials Engineering School of Engineering The University of Tokyo;

    Department of Prosthodontics School of Dentistry Showa University;

    Department of Prosthodontics School of Dentistry Showa University;

    Department of Materials Engineering School of Engineering The University of Tokyo;

    Department of Prosthodontics School of Dentistry Showa University;

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