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首页> 外文期刊>AIDS care. >Moderate intensity exercise training reverses functional aerobic impairment in HIV-infected individuals
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Moderate intensity exercise training reverses functional aerobic impairment in HIV-infected individuals

机译：中等强度的运动训练可逆转HIV感染者的有氧运动功能障碍

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HIV infection and HIV drug therapies result in physical and psychological challenges to those living with HIV. These conditions contribute to decreased functional aerobic capacity (FAC). The aim of this study was to determine the effects of a combined moderate-intensity aerobic and resistance exercise intervention on the FAC of HIV-infected individuals. Forty HIV-infected individuals were randomized to an exercise group (EX) who completed six weeks of moderate-intensity exercise training, or to a control group (CON) that did not receive the exercise intervention. Twice weekly, the EX group completed 30 minutes of moderate-intensity aerobic training followed by moderate-intensity resistance training. Prior to, and following, the intervention the FAC for each subject was determined by graded exercise treadmill stress test (GXT). At baseline testing, the mean FAC as determined by treadmill time-based estimation of maximal oxygen consumption was 25% below age-predicted values, a level of reduction indicating the presence of functional aerobic impairment (FAI). Following the intervention, the EX had a significant increase in time to fatigue and estimated VO2 max (p<.001). Further, FAI was eliminated (1% above age predicted values) during the exercise training. The EX group also experienced decreased heart rates during Stages 1 (p=.02), 2 (p=.01), 4 (p=.05) and 6 (p=.02) of the GXT. The CON had no significant changes during the intervention period. These data indicate that six weeks of combined moderate-intensity aerobic and resistance training can improve FAC and eliminate FAI in those with HIV. Results suggest that the functional limitations common in HIV-infected individuals are due in part to detraining that is reversible through moderate exercise adherence.
机译：艾滋病毒感染和艾滋病毒药物疗法给艾滋病毒携带者带来身体和心理挑战。这些条件导致功能性有氧能力（FAC）下降。这项研究的目的是确定中等强度的有氧运动和抵抗运动联合干预对HIV感染者FAC的影响。 40名受HIV感染的患者被随机分为完成六周中等强度运动训练的运动组（EX）或未接受运动干预的对照组（CON）。 EX组每周两次完成30分钟的中等强度有氧训练，然后进行中等强度的阻力训练。之前和之后，通过分级运动跑步机压力测试（GXT）确定每个受试者的FAC干预。在基线测试中，通过跑步机基于时间的最大耗氧量估算得出的平均FAC比年龄预测值低25％，降低水平表明存在功能性有氧障碍（FAI）。干预后，EX的疲劳时间显着增加，并且估计的VO2 max（p <.001）。此外，在运动训练中消除了FAI（比年龄预测值高1％）。 EX组在GXT的第1阶段（p = .02），第2阶段（p = .01），第4阶段（p = .05）和第6阶段（p = .02）时心率也下降。 CON在干预期间没有明显变化。这些数据表明，中强度有氧训练和抵抗训练相结合的六周训练可以改善HIV感染者的FAC并消除FAI。结果表明，在HIV感染者中常见的功能限制部分归因于通过适度的运动坚持可以逆转的训练。

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