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首页> 外文期刊>AIDS care. >Knowledge and acceptability of alternative HIV prevention bio-medical products among MSM who bareback.
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Knowledge and acceptability of alternative HIV prevention bio-medical products among MSM who bareback.

机译：精打细算的男男性接触者中艾滋病预防生物医学替代产品的知识和可接受性。

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Condom use is the best available strategy to prevent HIV infection during sexual intercourse. However, since many people choose not to use condoms in circumstances in which HIV risk exists, alternatives to condom use for HIV prevention are needed. Currently there are several alternative bio-medical HIV-prevention products in different stages of development: microbicides, vaccines, post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP). Seventy-two men who have sex with men (MSM) who took part in a study on Internet use and intentional condomless anal intercourse were asked about these four products during a semi-structured interview. The questions explored knowledge and acceptability of all the products and willingness to participate in microbicide and vaccine trials. Qualitative analysis of the data suggests that these men had virtually no knowledge of PrEP, very limited knowledge of microbicides, some information about PEP and considerably more knowledge about vaccines. Reactions towardsthe products were generally positive except for PrEP, for which reactions were polarized as either enthusiastic or negative. With the exception of PrEP, many men expressed willingness to use the products in the future. Most men would be willing to participate in trials for microbicides and vaccines if given basic reassurances. Concerns over negative side effects and preoccupation with possible infection were some of the motives given for non-willingness to participate in a vaccine trial. These results should inform the development of future trials of biomedical prevention products.
机译：使用避孕套是预防性交期间感染艾滋病毒的最佳策略。但是，由于许多人选择在存在HIV风险的情况下不使用安全套，因此需要替代使用安全套来预防HIV的方法。当前，在不同的发展阶段，有几种替代的生物医学预防HIV产品：杀菌剂，疫苗，暴露后预防（PEP）和暴露前预防（PrEP）。在半结构式访谈中，询问了参与互联网使用和有意无避孕套肛门性交研究的72名男同性恋者（MSM）。这些问题探讨了所有产品的知识和可接受性，以及参加杀微生物剂和疫苗试验的意愿。对数据的定性分析表明，这些人实际上不了解PrEP，对杀微生物剂的了解非常有限，有关PEP的一些信息以及有关疫苗的更多知识。除PrEP外，对产品的反应通常为阳性，而PrEP的反应被分为积极或消极两极化。除PrEP之外，许多男人表示愿意将来使用这些产品。如果有基本的保证，大多数男人愿意参加杀微生物剂和疫苗的试验。对负面副作用的关注以及对可能感染的关注是一些不愿意参加疫苗试验的动机。这些结果将为生物医学预防产品的未来试验提供参考。

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